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- PublicationOpen AccessExperiencias de mujeres víctimas de violencia de género digital: un análisis cualitativo(Universidad de Alicante, 2026) Samara López Yepes; López Barranco, Pedro José; Segura López, Gabriel; Suárez Cortés, María; Jiménez Ruiz, Ismael; EnfermeríaObjetivo: explorar las experiencias de mujeres víctimas de violencia digital por parte de sus parejas o exparejas. Metodología: Estudio cualitativo mediante tres grupos focales con 20 mujeres de entre 18 y 39 años. El análisis de datos se realizó mediante el software Atlas.ti, y el estudio contó con la aprobación del comité ético de la Universidad de Murcia. Resultados: Los resultados revelan que estas mujeres experimentan una pérdida significativa de privacidad y control debido al acceso no autorizado a dispositivos, la vigilancia mediante contraseñas compartidas, la geolocalización y la presión para responder constantemente a mensajes. Este tipo de cibercontrol lleva a un deterioro en su calidad de vida, causando ansiedad, depresión, aislamiento social y, en casos extremos, pensamientos suicidas. Además, la violencia digital no solo tiene impacto virtual, sino que se traduce en consecuencias psicológicas y sociales reales. Conclusión: las mujeres enfrentan una situación de vulnerabilidad en redes sociales, lo que requiere mayor atención y estrategias de intervención para prevenir este tipo de violencia.
- PublicationOpen AccessLa Escuela Oficial de Matronas de Santa Cristina en Madrid: referente de la formación profesional de las Matronas en España (1924-1953)(Universidad de Alicante (España), 2026-07-02) Segura López, Gabriel; Giménez Andreu, María del Rosario; Cayuela Fuentes, Pedro Simón; Vera Pérez, José Antonio; EnfermeríaIntroducción: El artículo examina la trayectoria histórica de la Escuela Oficial de Matronas de Santa Cristina en Madrid, fundada en 1917. Este centro fue pionero en la profesionalización de la enfermería obstétrica en España, contribuyendo de manera significativa a la formación de matronas y a la mejora de la salud materno-infantil. Se ha partido del objetivo de estudiar y analizar los hitos más relevantes en la evolución de la Escuela Oficial de Matronas de Santa Cristina, evaluando su impacto en la formación sanitaria y la implementación de políticas de salud pública en España. Metodología: Se utilizó una revisión documental basada en fuentes históricas, archivos institucionales y literatura académica. Se describieron los aspectos clave de su fundación, desarrollo, reformas educativas y su posterior integración al sistema universitario. Resultados: El análisis destaca cómo la Escuela, vinculada a la Maternidad de Santa Cristina, brindó una formación avanzada y práctica en obstetricia, incorporando avances científicos y tecnológicos a lo largo de su existencia. Enfrentó desafíos derivados de cambios políticos, presupuestarios y educativos. Su integración al sistema universitario en el siglo XX consolidó su prestigio, garantizando la continuidad de su legado. Conclusiones: La Escuela Oficial de Matronas de Santa Cristina cumplió un papel fundamental en la modernización de la obstetricia en España. Su contribución a la formación de profesionales y al fortalecimiento de la salud pública sigue siendo un referente histórico en la educación y práctica de los cuidados materno-infantiles.
- PublicationOpen AccessFolate fortification of white and whole-grain bread by adding Swiss chard and spinach. Acceptability by consumers(Elsevier, 0016-05-14) López Nicolás, Rubén; Frontela Saseta, María del Carmen; González-Abellán, Raquel; Barado-Piqueras, Ana; Perez-Conesa, Darío; Ros Berruezo, Gaspar; Tecnología de Alimentos, Nutrición y BromatologíaThe aim of this work was to study the effect of bread-making on the content of endogenous folate of white and whole-grain bread fortified with either Swiss chard or spinach at 20 g/100 g and 40 g/100 g measured by HPLC (H4-folate and 5-CH3-H4-folate); and to assess the sensory acceptability of folatefortified breads compared to non-fortified breads. The fortification of breads with 20 g/100 g and 40 g/100 g vegetables significantly (p < 0.001) increased the total folate content (from 19.9 to 57.9 mg/ 100 g in white bread and from 37.4 to 75.5 mg/100 g in whole-grain bread). Moreover, 40 g/100 g Swiss chard- and spinach-fortified breads obtained higher scores in overall acceptability than 20 g/100 g fortified or control bread for both white and whole-grain breads. The consumption of two servings (56 g each) per day of 40 g/100 g fortified bread would meet the daily folate requirements by 14.3e21.8% in adults and 9.6e14.5% in some special states like women of child-bearing age.
- PublicationOpen AccessSatiety hormone secretion induced by a carob-based formulation (Csat®) after simulated gastrointestinal digestion and colonic fermentation in STC-1 cells(Elsevier, 0001-07-26) Benito-Vázquez, Iván; Rosell, María de los Ángeles; Lates-Profir, Natalia; Díez Municio, Marina; Moreno, Francisco Javier; Frontela Saseta, María del Carmen; López Nicolás, Rubén; Tecnología de Alimentos, Nutrición y BromatologíaCsat® is a carob-derived based product standardized in galactomannans, inositols, and gallic acid, with potential applications in weight management and metabolic health. This study evaluated the effects of Csat® on satietyrelated enteroendocrine signalling after simulated gastrointestinal digestion and colonic fermentation. A standardized INFOGEST in vitro digestion model was combined with batch colonic fermentation using human faecal inoculum, and the resulting fractions were tested in STC-1 cells to quantify glucagon-like peptide-1 (GLP-1) and cholecystokinin (CCK) secretion. Digestive stability of key bioactive compounds was assessed by HPLC-MS. Undigested Csat® did not stimulate hormone secretion, whereas gastric digestion induced the strongest enteroendocrine response, significantly increasing both GLP-1 and CCK release. The intestinal soluble phase maintained a moderate stimulatory effect. During colonic fermentation, galactomannans were extensively degraded, while pinitol remained stable and gallic acid showed variable recovery. Fermentation kinetics revealed active microbial metabolism, with early fermentation associated with the highest endocrine response. GLP-1 and CCK secretion peaked at 4 h fermentation and progressively declined at later stages. Overall, Csat® showed a marked phase-dependent endocrine activity, with gastrointestinal processing and early microbial fermentation generating the most bioactive fractions. These findings support the potential of Csat® to modulate satiety-related pathways through coordinated digestion- and microbiota-derived mechanisms.
- PublicationRestrictedSupplementation of infant formulaswith recombinant human lactoferrin and/or galactooligosaccharides increases iron bioaccessibility as measured by ferritin formed in Caco-2 cell model(Elsevier, 2016-08-24) Aly, Esmat; Darwish, Aliaa Ali; López Nicolás, Rubén; Frontela Saseta, María del Carmen; Ros Berruezo, Gaspar; Tecnología de Alimentos, Nutrición y BromatologíaRecently, lactoferrin (Lf), a glycoprotein belonging to transferrin family, has received more attention for the discovery of its wide spectrum of functionalities. Among its important functionalities is its ability to bind Fe and its high stability against in vitro digestion. Galactooligosaccharides (GOS) also has functionality related to Fe bioaccessibility and it also positively affect Lf stability. This study aimed to evaluate the functionality of recombinant human Lf (rhLf) and GOS as factors that improve iron bioaccessibility in human milk. In this study, rhLf and GOS were added to First Infant Formula (FIF) in three concentrations (0.10, 0.15 and 0.20 and 3.3, 5 and 10 g 100 mL−1 of the reconstituted formula, respectively), whether alone or in combination. In vitro digestion model was applied to different infant formulas to evaluate Fe solubility and the obtained digests were added to Caco-2 cell line to determine Fe bioaccessibility through themeasurement of synthesized ferritin. The obtained results revealed that supplementation of formulas with rhLf and GOS enhanced Fe solubility to 66–97% which turns in an improvement of Fe bioaccessibility. Caco-2 cell ferritin content ranged from6 to 46 ng per mgcell protein with 5–7.5 fold increases in cells incubated with digested samples containing both rhLF and GOS. Although mineral solubility is the most important factor, which affects on Fe bioaccessibility, other factorsmay also interfere with it, such as the expression of divalent metal transporter 1 (DMT1). The findings also revealed that rhLf is a highly stable protein, especially in the presence of GOS and more researches are needed to clarify this hidden effect of GOS. Thus, rhLf and GOS together are prominent components of human milk could improve Fe bioaccessibility and it is noteworthy that these findingmust be taken into account during infant formula evolution to prevent some disease related to Fe deficiency.