Publication: p38 inhibitors for the treatment and prophylaxis of live cancer
Authors
Sabio, Guadalupe ; Tomas-Loba, Antonia ; Martinez Gil, Ana ; Gil Ayuso-Gontan, Carmen ; Gonzalez-Teran, Barbara ; Manieri, Elisa
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Publisher
World Intellectual Property Organization, International Bureau
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DOI
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info:eu-repo/semantics/patent
Description
International Publication Number: WO 2016/198698 A3
(WIPO/PCT)
Abstract
The present invention provides p38 inhibitors which are useful for the treatment and/or prophylaxis of liver cancer.
In particular, the present invention provides compounds capable of inhibiting the intracellular expression of the p38 gamma protein
in the hepatocytes of a subject relative to that observed in the absence of the compound, for use in the therapeutic treatment of liver
cancer.
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