Publication: Canine carcinosarcomas in the head
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Date
2005-11
Authors
Sánchez, J. ; Buendía, A. J. ; Villafranca, M. ; Velarde, R. ; Altamira, J. ; Martínez Cáceres, Carlos Manuel ; Navarro, J. A.
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Publisher
SAGE Publications
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DOI
https://doi.org/10.1354/vp.42-6-828
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info:eu-repo/semantics/article
Description
© 2005 American College of Veterinary Pathologists. This document is the Published version of a Published Work that appeared in final form in Veterinary Pathology. To access the final edited and published work see https://doi.org/10.1354/vp.42-6-828
Abstract
Four cases of neoplasms in the heads of old dogs were studied. All the dogs showed both carcinomatous and sarcomatous malignant components in an admixed growing pattern. Histologic analysis of the tumors showed that the carcinomatous cells resembled squamous cell carcinoma in all dogs except one, where an adenoid arrangement of the neoplastic cells was also observed. The sarcomatous component showed osteoid matrix produced by pleomorphic poorly differentiated cells, which is regarded as a typical feature of osteosarcomas. Immunohistochemical analysis demonstrated that the components were positive only for cytokeratin (carcinomatous component) or vimentin (sarcomatous component). This observation led us to classify the neoplasms as true carcinosarcomas, thus providing evidence of a new preferential location for this unusual tumor in dog.
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Citation
Veterinary Pathology, 2005, Vol. 42, Issue 6, pp. 828 - 833
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