Publication: Iron and calcium availability from digestion of infant cereals by Caco-2 cells
Authors
Frontela Saseta, María del Carmen ; Ros Berruezo, Gaspar ; Martínez Gracia, Carmen
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Publisher
Springer Nature
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DOI
10.1007/s00217-008-0990-z
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info:eu-repo/semantics/article
Description
Abstract
An adequate mineral intake during infancy is needed for normal growth and development. This study investigated the eVect of dephytinization of four infant cereals and the use of water and follow-on formula as the liquid of reconstitution on the intestinal cell uptake of iron and calcium from infant cereals using a model that combines a simulated gastrointestinal digestion adapted to the gastrointestinal conditions of infants younger than 6 months and the Caco-2 cell line. Iron and calcium uptake by Caco-2 cells from most infant cereals was signiWcantly (p < 0.05) improved when a phytase was added. When infant cereals were reconstituted with water, dephytinization increased iron (3.2–19.5 vs. 3–10%) and calcium (0.66–2.3 vs. 0.35–0.59%) availability compared to the same infant cereals reconstituted with a follow-on formula. We can conclude that dephytinization of infant cereals and water addition improved iron and calcium availability, depending on the infant cereal used.
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Citation
Frontela, C., Ros, G. & Martínez, C. Iron and calcium availability from digestion of infant cereals by Caco-2 cells. Eur Food Res Technol 228, 789–797 (2009). https://doi.org/10.1007/s00217-008-0990-z
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