Histology and histopathology Vol. 5, nº 1 (1990)

Ir a Estadísticas

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    Morphological studies of cytotoxic lesions in reversible endotoxic shock
    (Murcia : F. Hernández, 1990) García, R.; Díaz-Laviada, l.; Bosch, M.A.; Abarca, S.; Portolés, M.T.; Risco, C.; Ainaga, M.J.; Pagani, R.; Municio, A.M.; Escalona, J.
    Reversible endotoxic shock was induced in adult rats by intravenous injection of E. coli Olll:B4 lipopolysaccharide (LPS) and the progression of metabolic and morphological alterations was evaluated. Serum samples and biopsies from adrenal gland, liver and lung were studied at different times after LPS injection. Histological changes in these tissues were observed after endotoxin administration, coinciding with both the acute-phase and the recovery-phase of shock (24-72h after LPS injection). Signs of tissue regeneration can be correlated with the regression of some serum parameters to their normal values. Al1 these results indicate that in this experimental model of endotoxic shock, a reversible status was established, which will allow further studies of the endotoxic pathophysiological mechanisms in vivo, avoiding the complexity of the non-reversible process.
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    Cytoarchitecture of the dorsal lateral geniculate nucleus in the rabbit
    (Murcia : F. Hernández, 1990) Carmona Martos, R.; Abadía Molina, F.; Calvente Iglesias, R.; Abadía Fenoll, F.
    The cytoarchitecture and morphometry of the neurons in the a, sector of the dorsal lateral geniculate nucleus of the rabbit have been studied. The preparation techniques used were those of Golgi-Adams and Klüver-Barrera. Our method was to subdivide the a, sector into three zones (superior, media1 and inferior) and then to cut each zone along the horizontal, transverse and saggital planes in order to obtain precise measurements and descriptions of the neurons whatever their orientation. Differences exist in both the size and distribution of neurons in the inferior zone of the a, sector compared to the other two.
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    Postnatal development of the dog pineal gland. Light microscopy
    (Murcia : F. Hernández, 1990) Calvo, J.L.; Boya, J.; García-Mauriño, A.; López Carbonell, A.
    The light microscopical morphology of the dog pineal gland from the first postnatal day to maturity is described. In the first postnatal week, the pineal parenchyma shows immature cells and many mitotic figures. In this week, pigmented cells are obsemed for the first time, both in the pineal gland and in extrapineal nodules. Throughout the second week, the pineal parenchyma shows a cordonal pattern that disappears progressively in the following stages. From the 20-30th day onward, it is feasible to discern the cell types characteristic for the adult pineal gland. In the adult animals, the length of the pineal gland axes almost quadruplies that of the pineal gland in neonatal stages. The light microscopical features of the adult dog pineal gland are also described.
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    Ultrastructure of the parathyroid gland
    (Murcia : F. Hernández, 1990) Hideo Isono; Shizuko Shoumura; Shoichi Emura
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    Vasopressinergic neurons and the associated blood vessels in the rat anterior hypothalamus, an immunohistochemical study
    (Murcia : F. Hernández, 1990) Ray, Prajnan K.; Roy Choudhury, S.
    The paraventricular (PVN) and supraoptic (SON) nuclei of the hypothalamic neurosecretory system have been extensively investigated by many workers. The functional aspects of vasopressin secretion (elaborated by the PVN and SON neurons) in relation to the vasculature of the anterior hypothalamus are also well documented. However, the available data concerning vasopressin (VP) functions are largely based on physiological studies. Corroborative morphological correlation with regard to this has received little attention. The present report elucidates the intricate anatomical relationships between the VP-neurons and the adjoining capillaries in the rat anterior hypothalamus. A peroxidase-antiperoxidase (PAP) immunocytochemical study, using a commercial VP antibody, was carried out for this purpose. The observations are interpreted from a functional standpoint. VP-immunostained elements, i.e. the somata and the processes (mainly dendrites), were localized (i) close to the wall, (ii) on the endothelium, and (iii) occasionally, in the lumen of the hypothalamic capillaries. The findings provide immunocytochemical evidence that the vasopressinergic elements are in direct relationship with the hypothalamic vasculature. This raises some interesting possibilities for the former to be involved in: (i) affecting the permeability of the blood-brain barrier for transport of various nutrient substances (important in aging and Alzheimer's disease), (ii) inducing an alteration in the water permeability of the brain vessels on which depends the precise adjustment of brain water content and of brain volume (fundamental to normal functioning of the brain), and (iii) serving as osmoreceptors of the blood flowing through the capillaries and thus providing a feedback mechanism for VP modulation.