Recent progress in macrophage- mediated tendon injury and healing
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Date
2026
Authors
Yining Zhang
Yanzhao Dong
Xiaodi Zou
Ahmad Alhaskawi
Fangyu Yi
Sohaib Hasan Abdullah Ezzi
Vishnu Goutham Kota
Mohamed Hasan Abdulla Hasan Abdulla
Haiying Zhou
Alenikova Olga
Journal Title
Journal ISSN
Volume Title
Publisher
Universidad de Murcia, Departamento de Biologia Celular e Histiologia
Abstract
Recently, the role of macrophages in tendon repair has received increased attention. These cells are versatile, playing multiple roles, such as defending the host, engulfing debris, producing growth factors, and releasing substances that can both promote and alleviate inflammation. Within the scope of tendon repair and tendinopathy resolution, macrophages are essential contributors. However, the current understanding of macrophage involvement in tendon healing remains limited. Hence, understanding macrophages' impact on tendon healing is of considerable importance for devising innovative treatment approaches. It is crucial to examine the precise role that macrophages play in tendon recovery, as it provides new understanding that can propel both research and the development of therapeutic methods aimed at enhancing tendon recovery moving forward
Description
Keywords
Macrophage , Tendinopathy , Tendinopathy heal , Polarization , Tendon
Citation
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