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A systematic review of the cardiometabolic benefits of plant products containing mixed phenolics and polyphenols in postmenopausal women: insufficient evidence for recommendations to this specific population

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dc.contributor.authorSánchez-Martínez, Lorena
dc.contributor.authorPeriago, María Jesús
dc.contributor.authorGarcía-Alonso, Javier
dc.contributor.authorGarcía-Conesa, María Teresa
dc.contributor.authorGonzález-Barrio, Rocío
dc.contributor.departmentTecnología de Alimentos, Nutrición y Bromatología
dc.date.accessioned2025-01-28T08:37:14Z
dc.date.available2025-01-28T08:37:14Z
dc.date.issued2021-11-27
dc.description© 2021 by the authors. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/. This document is the Published version of a Published Work that appeared in final form in Nutrients. To access the final edited and published work see https://doi.org/10.3390/nu13124276
dc.description.abstractMenopause is a critical stage in a woman’s life in which cardiometabolic alterations appear, such as insulin resistance or a predisposition to visceral fat deposits, leading to an increased risk of cardiometabolic diseases (R-CMBs). New strategies to reduce the R-CMBs in postmenopausal women using natural compounds without adverse effects are desirable. In this sense, plant-based diets rich in fruits and vegetables could play a fundamental role due to the high content of bioactive compounds found in these diets, such as (poly)phenols, known for their antioxidant, anti-inflammatory and vasodilator properties. The aim of this research was to carry out a dietary trial to evaluate the effect of the daily intake of different (poly)phenol-rich foods (PP-rich foods) for 2 months on the modulation of the main cardiometabolic risk biomarkers of postmenopausal women. The results showed a slight improvement in blood pressure (BP), lipid profile and oxidative stress, endothelial function and inflammatory biomarkers. These findings suggest that daily consumption of PP-rich foods alleviated the R-CMBs of postmenopausal women by reducing the oxidative stress and, thus, the risk of cardiovascular events; however, the magnitude of the cardioprotective effect of (poly)phenols depends on inter-individual variability.es
dc.formatapplication/pdfes
dc.format.extent26es
dc.identifier.doihttps://doi.org/10.3390/nu13124276
dc.identifier.eisbnNutrients 2021, 13, 4276es
dc.identifier.issnElectronic: 2072-6643
dc.identifier.urihttp://hdl.handle.net/10201/149397
dc.languageenges
dc.publisherMDPI
dc.relationFundación Séneca (Agencia de Ciencia y Tecnología de la Región de Murcia), Spain (20904/PI/2018).es
dc.relation.publisherversionhttps://www.mdpi.com/2072-6643/13/12/4276
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAntioxidantses
dc.subjectHOMA-IR
dc.subjectSystolic blood pressure
dc.subjectDiastolic blood pressure
dc.subjectTNF-α
dc.subjectCRP
dc.subjectIL-6
dc.subjectEndothelial cell adhesion biomarkers
dc.subjectOxidative stress biomarkers
dc.subject(Poly)phenols
dc.titleA systematic review of the cardiometabolic benefits of plant products containing mixed phenolics and polyphenols in postmenopausal women: insufficient evidence for recommendations to this specific populationes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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