Publication: Serotonin immunoreacmtivitiyn the carotid body of adult humans
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Date
1994
Authors
Habec, J. ; Pallot, D.J. ; Kummer, W.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The distribution of serotonin immunoreactivity
(-1R) was studied in adult human carotid bodies,
obtained at post-mortem, using both the peroxidaseantiperoxidase
method on paraffin sections and a doublelabelling
immunofluorescence on frozen sections.
Antibodies against synaptophysin and protein gene
product (PGP) 9.5 were used for identification of
serotonin-1R cells. Serotonin-1R was demonstrable in the
carotid bodies of adult humans and it was coexpressed
mostly with synaptophysin or PGP 9.5 in type 1 cells.
Some serotonin immunopositive type I cells were
located in close proximity to capillaries. Serotonin-IR
was also observed in a few endothelial cells.
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