Publication:
Mercury accumulation, structural damages, and antioxidant and immune status changes in the Gilthead Seabream (Sparus aurata L.) exposed to methylmercury

Simple item page
dc.contributor.authorGuardiola, F. A.
dc.contributor.authorChaves-Pozo, E.
dc.contributor.authorEspinosa, C.
dc.contributor.authorRomero, D.
dc.contributor.authorMeseguer, J.
dc.contributor.authorCuesta, A.
dc.contributor.authorEsteban Abad, María Ángeles
dc.contributor.departmentCiencias Sociosanitarias
dc.date.accessioned2024-03-12T09:06:03Z
dc.date.available2024-03-12T09:06:03Z
dc.date.issued2016-02-23
dc.description©2016 Springer. This document is the Published version of a Published Work that appeared in final form in Archives of Environmental Contamination and Toxicology. To access the final edited and published work see https://doi.org/10.1007/s00244-016-0268-6es
dc.description.abstractIn aquatic systems, mercury (Hg) is an environmental contaminant that causes acute and chronic damage to multiple organs. In fish, practically all of the organic Hg found is in the form of methylmercury (MeHg), which has been associated with animal and human health problems. This study evaluates the impact of waterborne-exposure to sublethal concentrations of MeHg (10 [mu]g L^sup -1^) in gilthead seabream (Sparus aurata). Hg was seen to accumulate in liver and muscle, and histopathological damage to skin and liver was detected. Fish exposed to MeHg showed a decreased biological antioxidant potential and increased levels of the reactive oxygen molecules compared with the values found in control fish (nonexposed). Increased liver antioxidant enzyme activities (superoxide dismutase and catalase) were detected in 2 day-exposed fish with respect to the values of control fish. However, fish exposed to MeHg for 10 days showed liver antioxidant enzyme levels similar to those of the control fish but had increased hepato-somatic index and histopathological alterations in liver and skin. Serum complement levels were higher in fish exposed to MeHg for 30 days than in control fish. Moreover, head-kidney leukocyte activities increased, although only phagocytosis and peroxidase activities showed a significant increase after 10 and 30 days, respectively. The data show that 30 days of exposure to waterborne MeHg provokes more significant changes in fish than a short-term exposure of 2 or 10 days.es
dc.embargo.termsSI
dc.formatapplication/pdfes
dc.format.extent13es
dc.identifier.citationArchives of Environmental Contamination and Toxicology, Vol. 70, N. 4, 2016, pp. 734-746
dc.identifier.doihttp://doi.org/10.1007/s00244-016-0268-6
dc.identifier.issnPrint: 0090-4341
dc.identifier.issnElectronic: 1432-0703
dc.identifier.urihttp://hdl.handle.net/10201/140140
dc.languageenges
dc.publisherSpringeres
dc.relationThe financial support of the Spanish Ministerio de Economía y Competitividad under Grant No. AGL-2011-30381-C03-01 and Fundación Séneca de la Región de Murcia (Spain) (Grant No. 19883/GERM/15, Grupo de Excelencia de la Región de Murcia)es
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s00244-016-0268-6es
dc.rightsinfo:eu-repo/semantics/embargoedAccesses
dc.subjectWater pollutiones
dc.subjectMercuryes
dc.subjectHuman exposurees
dc.subjectFishes
dc.subjectAntioxidantses
dc.subjectAnalysises
dc.subjectStudieses
dc.subjectSkines
dc.subjectApoptosises
dc.subjectEnzymeses
dc.subjectLIveres
dc.subjectImmune systemes
dc.subjectToxicityes
dc.subjectLeukocyteses
dc.titleMercury accumulation, structural damages, and antioxidant and immune status changes in the Gilthead Seabream (Sparus aurata L.) exposed to methylmercuryes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
23-Guardiola_et_al_2016.pdf
Size:
1.28 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.26 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Artículos