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Blind aspiration biopsy versus a guided hysteroscopic technique for investigation of the endometrium in infertile women

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dc.contributor.authorEjzenberg, Dani
dc.contributor.authorde Jesus Simões, Manuel
dc.contributor.authorPinheiro, Walter
dc.contributor.authorSoares Júnior, José Maria
dc.contributor.authorSerafini, Paulo Cesar
dc.contributor.authorChada Baracat, Edmund
dc.date.accessioned2021-10-27T07:21:13Z
dc.date.available2021-10-27T07:21:13Z
dc.date.issued2016
dc.description.abstractEmbryo implantation failure and recurrent abortion are common indications for endometrial evaluation to determine the implantation window and diagnose endometrial anomalies. There are few research studies comparing the efficacy of different techniques used for endometrial sampling in infertile females during the luteal phase. Likewise, morphometric studies of the endometrium through aspiration biopsy are scant. A cross-sectional study of 30 infertile and 10 fertile females was carried out. The study participants underwent hysteroscopic and aspiration biopsies (pipelle) at the midluteal phase. Computer-assisted morphometric and pathological anatomy analyses were conducted independently by two pathologists blinded to the study. The two endometrial sampling biopsy techniques were compared through morphometric and pathological anatomy analyses using three parameters: a) the amount of material collected for the endometrial studies; b) the scope and origin of sampled materials; and c) the quality of the sample. Both biopsy techniques produced sufficient material for analysis. The directed biopsies yielded higher quality samples from targeted segments of the uterine cavity because samples were homogeneous and had no architectural distortion (p<0.05). Blood was present only in the samples obtained through a Pipelle. Endometritis was detected in 10% of the infertile women. Our findings suggest that hysteroscopic biopsies are superior to blinded aspiration biopsieses
dc.formatapplication/pdfes
dc.format.extent6es
dc.identifier.citationHistology and Histopathology, Vol.31, nº9, (2016)
dc.identifier.doiDOI: 10.14670/HH-11-725
dc.identifier.issn0213-3911
dc.identifier.issn1699-5848
dc.identifier.urihttp://hdl.handle.net/10201/113403
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de Biología Celular e Histologíaes
dc.relationSin financiación externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectPiepelle biopsyes
dc.subjectHysteroscopic biopsyes
dc.subjectEndometriumes
dc.subjectInfertilyes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleBlind aspiration biopsy versus a guided hysteroscopic technique for investigation of the endometrium in infertile womenes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.31, nº9 (2016)