Publication: Matrix production of smooth muscle cells from rat aorta in vitro
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Date
1993
Authors
Stieme, B. ; Springmeier, G. ; El-Jarad, L. ; Schroter-Kermani, C.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Immunofluorescence microscopic methods
served to demonstrate the production of the following
matrix components in cultures of vascular smooth
muscle cells from rat aorta: fibronectin; nidogen;
heparan sulphate-proteoglycan (HS-PG); laminin; and
collagen types 1, 111, IV, V, and VI. A time-dependence
of synthesis and secretion could be shown for a number
of components of the extracellular matrix (ECM), such
as laminin. The results revealed the following estimated
quantitative differences of the collagen types: type 1 >
type 111 > types V and VI. A filamentouslfibrillar matrix
and also occasionally a typical basal lamina could be
demonstrated electron microscopically around the
smooth muscle cells.
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Citation
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