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Changes in salivary proteins can reflect beneficial physiological effects of ejaculation in the dog

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dc.contributor.authorMuñoz-Prieto, Alberto
dc.contributor.authorEscribano, Damián
dc.contributor.authorHorvatić, Anita
dc.contributor.authorContreras-Aguilar, María Dolores
dc.contributor.authorBernal, Luis
dc.contributor.authorRubić, Ivana
dc.contributor.authorCerón, Jose Joaquín
dc.contributor.authorDabrowski, Roman
dc.contributor.authorMrljak, Vladimir
dc.contributor.departmentMedicina y Cirugía Animal
dc.date.accessioned2024-02-10T00:07:45Z
dc.date.available2024-02-10T00:07:45Z
dc.date.issued2021-01-28
dc.description©2021 Elsevier Inc. All rights reserved. This document is the Published version of a Published Work that appeared in final form in Theriogenology. To access the final edited and published work see https://doi.org/10.1016/j.theriogenology.2021.01.017
dc.description.abstractThe objective of this study was to study the changes in salivary proteins that occur in the dog after the ejaculation process. Saliva samples from eight dogs before and after induced ejaculation were analyzed by proteomic using Tandem Mass Tag (TMT) labeling and LC-MS/MS analysis. A total of 33 salivary proteins showed significant changes after the ejaculation process. The up-regulated proteins that showed changes of higher magnitude were mucin-7 (MUC-7), peroxiredoxin-4 (PRDX4) and galectin-3 (LEGALS3) whereas proteins such as alpha-1-acid glycoprotein (A1G1) and alpha-1B-glycoprotein (A1BG) were the most down-regulated. MUC-7 and PRDX4 expression in saliva after ejaculation could be associated with the protective “environment” created by the organism to exert pr 3o-fertility activities and antioxidants benefits in spermatozoa. Also LEGALS3 increment could be associated with an improvement of wellbeing and could contribute to a positive global effect in the body. Down-regulations of A1G1 and A1GB proteins found in saliva after ejaculation could be associated with a reduction in systemic inflammation. Overall it can be concluded that, changes in proteins in saliva that are produced after ejaculation can reflect a state of increase immune defenses, improvement of antioxidant status and low inflammation.es
dc.embargo.termsSi
dc.formatapplication/pdfes
dc.format.extent7es
dc.identifier.doihttps://doi.org/10.1016/j.theriogenology.2021.01.017
dc.identifier.eisbnTheriogenology, volumen164es
dc.identifier.issnPrint: 0093-691X
dc.identifier.issnElectronic: 1879-3231
dc.identifier.urihttp://hdl.handle.net/10201/139185
dc.languageenges
dc.relationSin financiación externa a la Universidades
dc.rightsinfo:eu-repo/semantics/embargoedAccesses
dc.subjectSalivaes
dc.subjectDoges
dc.subjectEjaculationes
dc.subjectAntioxidantes
dc.subjectInflammationes
dc.titleChanges in salivary proteins can reflect beneficial physiological effects of ejaculation in the doges
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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