Publication:
A test of the predictive validity of QALYs using chronic and temporary time trade-off values

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Date
2004-02
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Authors
Abellán Perpiñán, José María ; Pinto Prades, José Luis ; Méndez Martínez, Ildefonso ; Badía Llach, Xabier
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Publisher
Elsevier
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Economía Aplicada
DOI
http://dx.doi.org/10.2139/ssrn.563327
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info:eu-repo/semantics/article
Description
© 2004 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Submitted version of a Published Work that appeared in final form in UPF Economics and Business Working Paper No. 741. To access the final edited and published work see http://dx.doi.org/10.2139/ssrn.563327
Abstract
This paper presents a test of the predictive validity of various classes of QALY models (i.e., linear, power and exponential models). We first estimated TTO utilities for 43 EQ-5D chronic health states and next these states were embedded in health profiles. The chronic TTO utilities were then used to predict the responses to TTO questions with health profiles. We find that the power QALY model clearly outperforms linear and exponential QALY models. Optimal power coefficient is 0.65. Our results suggest that TTO-based QALY calculations may be biased. This bias can be avoided using a power QALY model.
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Cost utility analysis , QALYs , Power QALY model , Predictive validity , Time tradeoff
Citation
SSRN Electronic Journal, 2004
URI
http://hdl.handle.net/10201/146988
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