Publication: Ultrastructure and light microscopical study
of a Leydig cell tumor of the testis associated
with bilateral gynaecomastia
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Date
1989
Authors
Muro, M. Moreno ; Menchero, S. Coca ; Pelegrín, J. A. Martos ; Hernández, A. Izquierdo
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Light and electronmicroscopic study of a
Leydig cell testicular tumor in an 18-year-old male is
presented. Bilateral gynaecomastia and normal hormonal
blood levels were found. Emphasis on the diagnostic
value of electronmicroscopy is remarked upon, based on
the following ultrastructural characteristics of the cells;
1) Ovoid shaped nuclei with ondulating contours
and dispersed and homogeneous chromatin, 2) Rich
agranular endoplasmic reticulum with frequent special
modifications, such as membranous whorls with a central
cytoplasmic mass or lipid droplets, 3) Numerous
mitochondria with occasional tubular cristae, 4) Numerous
lipid vacuoles. Other structures also identified in this
tumor are Reinke crystalloids, cytoplasmic microbodies,
myelin figures, gap-type junctional complexes and
paracrystalline inclusions of Payer type E, which are less
common.
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