Publication: Morphometric studies on the development of human thyroid gland in early fetal life
Loading...
Date
1992
Authors
Bocian-Sobkowska, J. ; Malendowicz, L.K. ; Woíniak, W.
item.page.secondaryauthor
item.page.director
Publisher
Murcia : F. Hernández
publication.page.editor
publication.page.department
DOI
item.page.type
info:eu-repo/semantics/article
Description
Abstract
Histological and morphometric studies were
performed on 30 thyroid glands obtained from normal
human fetuses. Their crown-rump length (CRL) ranged
from 57 to 190 mm, corresponding to the gestational
age of 10 - 20 weeks.
The weight of the thyroid gland increased proportionally
in relation to CRL, foot length and fetus
weight. The first follicles containing PAS-positive
colloid were observed in the peripheral part of the
thyroid gland of 57 mm CRL fetus. The number of
follicles per 1 mm2 of thyroid surface section increased
up to 85 mm CRL and thereafter gradually declined for
the end of studied period of fetal life. The volumes (in
mm3) of thyroid epithelium, colloid and stroma,
beginning from 85 mm increased proportionally to the
CRL while the height of epithelial cells did not change.
The epithelium/colloid ratio decreased notably to 165
mm CRL and thereafter remained constant.
Results of the present study suggest that the thyroid
gland of human fetus approaches structural maturity in
17.5 week of gestation.
publication.page.subject
Citation
item.page.embargo
Ir a Estadísticas
Sin licencia Creative Commons.