Publication:
Human lung fructose-1,6-bisphosphatase is localized in pneumocytes II

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Human lung fructose16bisphosphatase is localized in pneumocytes II.pdf(1.9 MB)
Date
2001
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Authors
Gizak, A. ; Rakus, D. ; Kolodziej, J. ; Zabel, M. ; Ogorzalek, A. ; Dzugaj, A.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The localization of fructose-1,6-bisphosphatase (Fru-1,6-Pase EC 3.1.3.11) in human alveolar epithelium was determined immunohistochemically using a polyclonal antibody raised against the enzyme purified from human liver. The immunohistochemical analysis revealed that the Fru-1,6-Pase was localized in pneumocytes 11 and was absent in pneumocytes 1. Hypothetically Fru-1,6-Pase participating in glucose-6-phosphate synthesis from noncarbohydrate precursors increases NADPH leve1 which is used for surfactant synthesis and for glutathione redox cycle.
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Immunocytochemistry , Pneumocytes
Citation
URI
http://hdl.handle.net/10201/20635
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Histology and histopathology Vol.16, nº 1 (2001)
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