Publication: Chitooligosaccharide promotes immune organ development in broiler chickens and reduces serum lipid levels
Authors
Shenghe, Li ; Erhui, Jin ; Enmei, Qiao ; Guozhong, Wu ; Kui, Li
item.page.secondaryauthor
item.page.director
Publisher
Universidad de Murcia. Departamento de BiologĂa Celular e HistologĂa
publication.page.editor
publication.page.department
DOI
DOI: 10.14670/HH-11-860
item.page.type
info:eu-repo/semantics/article
Description
Abstract
This study investigated the effects of
chitooligosaccharide on lipid metabolism, immune organ
development, and lymphocyte apoptosis in broiler
chickens. A total of 480 one-day-old broiler chickens
(Arbor Acres) were randomly and evenly assigned to
control group and experimental groups I, II, and III. The
control group was given a basic diet, while experimental
groups I, II, and III were given basic diets for 42 days,
supplemented with 50 mg/kg chlortetracycline, 20, and
40 mg/kg chitooligosaccharide, respectively. We found
levels of serum triglycerides (TG) and low density
lipoprotein cholesterol (LDL-C) to be significantly
reduced in experimental group II after 21 days, while the
periarterial lymphatic sheath area of the spleens and the
average number of bursa of Fabricius nodes were
markedly increased. The serum total protein (TP) and
high density lipoprotein cholesterol (HDL-C) levels,
bursa of Fabricius index, and bursa of Fabricius lobule
areas were additionally increased in experimental group
III. After 42 days, the serum TP content had also
increased and the bursa of Fabricius lobule area was
augmented as well in experimental group II. Moreover,
the splenic periarterial lymphatic sheath areas and the
average numbers of bursa of Fabricius nodes were
significantly increased in experimental group III. At both
21 and 42 days, numbers of Caspase-3 positive cells in
spleen and bursa of Fabricius were significantly
decreased in experimental groups II and III. Our results
show that appropriate supplementation of chitooligosaccharide may improve lipid metabolism, promote
immune organ development, and inhibit lymphocyte
apoptosis in broilers.
publication.page.subject
Citation
item.page.embargo
Ir a EstadĂsticas
Este Ătem está sujeto a una licencia Creative Commons. CC BY 4.0