Publication:
Inheritance of Refractive Error in Millennials

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dc.contributor.authorPusti, D.
dc.contributor.authorBenito, A.
dc.contributor.authorMadrid-Valero, J.J.
dc.contributor.authorOrdoƱana, J.R.
dc.contributor.authorArtal, P.
dc.contributor.departmentFĆ­sica
dc.date.accessioned2025-01-15T09:26:34Z
dc.date.available2025-01-15T09:26:34Z
dc.date.issued2020-05-18
dc.descriptionĀ© 2020 The authors This document is the published version of a published work that appeared in final form in Scientific Reports This document is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0 To access the final edited and published work see: https://doi.org/10.1038/s41598-020-65130-w
dc.description.abstractOver the last decades, the prevalence of myopia has suddenly increased, and at this rate, half of the world's population will be myopic by the year 2050. Contemporary behavioural and lifestyle circumstances, along with emergent technology, are thought to be responsible for this increase. Twin studies mostly reported a high heritability of refractive error across ethnicities. However, heritability is a population statistic and could vary as a result of changing environmental conditions. We studied the variance of refractive error in millennials with 100 twin pairs of university students in southeast Spain. The study population presented a high prevalence of myopia (77%). Statistical analysis showed the variance of refractive error in this group of young twins was mainly driven by the shared environment and, to a lesser extent, by additive genetic factors. We found an increase in myopia prevalence accompanied by a decrease in heritability in this sample of millennials in contrast with results from a previous generation group from the same ethnic origin.es
dc.formatapplication/pdfes
dc.format.extent9es
dc.identifier.doihttps://doi.org/10.1038/s41598-020-65130-w
dc.identifier.eisbnScientific Reports, volumen 10, nĆŗmero 1 (2020), artĆ­culo 8173.es
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/10201/148463
dc.languageenges
dc.publisherNature Researches
dc.relationThis study was supported by MyFUN: European Unionā€™s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 675137.es
dc.relation.publisherversionhttps://www.nature.com/articles/s41598-020-65130-w
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAtribuciĆ³n 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectMyopiaes
dc.subjectTwins
dc.subjectInheritance
dc.subjectEnvironmental exposure
dc.titleInheritance of Refractive Error in Millennialses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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