Publication: Mature congenital intraneural teratoma in cerebellum of pig
Authors
Soto Domíngue, Adolfo ; Rodríguez Rocha, Humberto ; García García, Aracely ; Saucedo Cárdenas, Odila ; Rodríguez Tovar, Luis E. ; Castillo Velázquez, Uziel
item.page.secondaryauthor
item.page.director
Publisher
Universidad de Murcia. Departamento de Biología Celular e Histología
publication.page.editor
publication.page.department
DOI
DOI: 10.14670/HH-18-034
item.page.type
info:eu-repo/semantics/article
Description
Abstract
The biological behavior of teratomas
depends on several interdependent clinical and
epidemiological variables such as age at diagnosis, sex,
tumor microenvironment, and tumor morphology,
among others. All these variables are correlated to
different cytogenetic and molecular aberrations (Harms
et al., 2006). There are null reports of teratomas in pigs.
The aim of this study was to characterize the tissues
present in a mature congenital intraneural teratoma in the
cerebellum area of a Landrace female pig of 6-7 weeks
old. In this study, tissue control samples were used to
validate each staining method. Sections from the
teratoma showed normal histology of the cerebellum,
including rounded Purkinje neurons with abundant
cytoplasm, euchromatic nuclei, and prominent nucleoli;
glial cells with a scarce amount of cytoplasm and small
and highly basophile-nuclei (compact chromatin) and
axonal tracts (white matter). Interestingly, we also
observed areas with tissues different from the nervous
tissue, including bundles of well-defined skeletal muscle
fibers with a striated pattern and peripheral nuclei;
hyaline cartilage plaques, with prominent presence of
chondrocytes in their lagoons forming isogenous groups
surrounded by a territorial and interterritorial matrix;
trabeculated bone tissue; and adipocytes, which are ringshaped cells with peripheral flattened nuclei, as a result
of the presence of a central large lipid droplet. To our
knowledge, this study is the first to describe a congenital
intraneural mature teratoma in the cerebellum of a pig.
publication.page.subject
Citation
item.page.embargo
Ir a Estadísticas
Este ítem está sujeto a una licencia Creative Commons. CC BY 4.0