Abnormal distribution of CD45 isoforms expressed 
by CD4+ and CD8+ T cells in rheumatoid arthritis

Publication:
Abnormal distribution of CD45 isoforms expressed by CD4+ and CD8+ T cells in rheumatoid arthritis

dc.contributor.author	Mamoune, A.	es
dc.contributor.author	Durand, V.	es
dc.contributor.author	Le Goff, P.
dc.contributor.author	Pennec, Y.L.
dc.contributor.author	Youinou, P.
dc.contributor.author	Le Corre, R.
dc.date.accessioned	2011-02-22T11:21:22Z
dc.date.available	2011-02-22T11:21:22Z
dc.date.issued	2000
dc.description.abstract	CD45RO+ T cells are referred to as memory or helper-inducer while CD45RA+ T cells are regarded as naive or suppressor-inducer T cells. The former population predominates in the peripheral blood and even more in the synovial fluid of patients with rheumatoid arthritis, to the expense of the latter population. Within the CD45RB+ compartment, there appears to be more of the fully-differentiated than of the early-differentiated CD4+ T cells. In spite of the fact that these lymphocytes are close to undergoing apoptosis, this programmed cell death is inhibited in the rheumatoid synovium.	es
dc.format	application/pdf	es
dc.format.extent	5	es
dc.identifier.issn	0213-3911	es
dc.identifier.uri	http://hdl.handle.net/10201/19311
dc.language	eng	es
dc.publisher	Murcia : F. Hernández	es
dc.relation.ispartof	Histology and histopathology	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Rheumatoid arthritis	es
dc.subject	Apoptosis	es
dc.subject.other	CDU::6 - Ciencias aplicadas::61 - Medicina	es
dc.title	Abnormal distribution of CD45 isoforms expressed by CD4+ and CD8+ T cells in rheumatoid arthritis	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es

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