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Association of sinus histiocytosis with massive lymphadenopathy and idiopathic hypereosinophilic syndrome

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dc.contributor.authorHernández, Dimases
dc.contributor.authorGutierrez, Luises
dc.contributor.authorDuque, Herminia
dc.contributor.authorOlavarria, Renato
dc.contributor.authorMuci, Rafael
dc.contributor.authorWunaii, Herman
dc.date.accessioned2011-01-17T12:40:15Z
dc.date.available2011-01-17T12:40:15Z
dc.date.issued1987
dc.description.abstractA patient was evaluated because of edema, pruritus and generalized painless lymphadenopathy. Laboratory tests showed marked eosinophilia without known etiology. CT scan of abdomen revealed multiple lymph nodes in retroperitoneal area. Lymph node biopsy was reported as sinus histiocytosis, bone marrow biopsy showed hipercellularity with marked infiltration of normal eosinophils. During his admission he developed Coombs positive hemolytic anaemia. Once he was stable, a laparotomy was performed and the patient died two days later because of septic shock. Autopsy revealed sinus histiocytosis with massive lymphadenopathy (SHML) with extranodal involvement of duodenum, spleen and prostate; septic liver and spleen, pyelonephritis, marked infiltration of eosinophilis in lymph nodes, spleen, liver duodenum and lungs. To the best of our knowledge, this is the first case report of the association of SHML and Idiopathic Hypereosinophilic Sundrome (HES) .
dc.formatapplication/pdfes
dc.format.extent4es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/17890
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectSinus histiocytosises
dc.subjectHypereosinophilic syndromees
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleAssociation of sinus histiocytosis with massive lymphadenopathy and idiopathic hypereosinophilic syndromees
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 2, nº 3 (1987)