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Endocrine disruptors and attention deficit hyperactivity disorder: a systematic review

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dc.contributor.authorLópez-García, Marta
dc.contributor.authorMartínez-Bebia, Manuel
dc.contributor.authorLópez-Moro, Alejandro
dc.contributor.authorGiménez-Blasi, Nuria
dc.contributor.authorLatorre, José Antonio
dc.contributor.authorMariscal-Arcas, Miguel
dc.contributor.departmentTecnología de los Alimentos, Nutrición y Bromatologíaes
dc.date.accessioned2025-06-24T06:54:55Z
dc.date.available2025-06-24T06:54:55Z
dc.date.issued2025-06-21
dc.description© 2025 The Author(s). This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/. This document is the Published version of a Published Work that appeared in final form in Archives of Medical Research. To access the final edited and published work see https://doi.org/10.1016/j.arcmed.2025.103260es
dc.description.abstractThe increasing prevalence of attention deficit hyperactivity disorder (ADHD) in children has prompted more research on both genetic and environmental risk factors, including endocrine-disrupting chemicals (EDCs) such as bisphenol A (BPA) and polychlorinated biphenyls (PCBs). This review focuses on studies published between 2013 and December 2023 that explore the potential impact of BPA and PCBs on ADHD. The review draws from databases such as WOS, PubMed, and Scopus. BPA, a chemical commonly used in plastics and resins, has raised concerns due to its potential neurodevelopmental effects, particularly when exposure occurs prenatally. Multiple studies have suggested an association between prenatal BPA exposure and an increased risk of ADHD in offspring, though more research is needed. Similarly, PCBs, which are persistent environmental pollutants primarily found in contaminated food sources, have been linked to cognitive and behavioral issues, including attention deficits and hyperactivity. Both BPA and PCBs have been shown to disrupt neurodevelopment, underscoring the importance of regulating these chemicals to safeguard children’s health. While these findings highlight a potential risk, further studies are required to clarify the underlying mechanisms and the precise role these EDCs play in the development of ADHD and other neurobehavioral disorders.es
dc.formatapplication/pdfes
dc.format.extent16es
dc.identifier.doihttps://doi.org/10.1016/j.arcmed.2025.103260
dc.identifier.eisbnArchives of Medical Research 56 (2025) 103260es
dc.identifier.issnPrint: 0188-4409
dc.identifier.issnElectronic: 1873-5487
dc.identifier.urihttp://hdl.handle.net/10201/156446
dc.languageenges
dc.publisherElsevieres
dc.relationThis paper will be part of Alejandro Lopez-Moro’s doctoral thesis. It is being completed as part of the “Nutrition and Food Sciences Program” at the University of Granada. Spain.es
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0188440925000803?via%3Dihubes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAttention deficit hyperactivity disorderes
dc.subjectADHDes
dc.subjectBPAes
dc.subjectEDCses
dc.subjectPCBes
dc.titleEndocrine disruptors and attention deficit hyperactivity disorder: a systematic reviewes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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