Publication:
ImmunohistochemicaI-morphometric study of the LH-adenohypophyseal cells following chronic treatment with met-enkephalin

Thumbnail Image
Files
ImmunohistochemicaImorphometric study of the LHadenohypophyseal cells following chronic treatment with metenkephalin.pdf(287.22 KB)
Date
1994
relationships.isAuthorOfPublication
relationships.isSecondaryAuthorOf
relationships.isDirectorOf
Authors
Rubio, M. ; Sanchez, F. ; Carretero, J. ; Riesco, J. M. ; Cabo, L. ; Vazquez, R.
item.page.secondaryauthor
item.page.director
Publisher
Murcia : F. Hernández
publication.page.editor
publication.page.department
DOI
item.page.type
info:eu-repo/semantics/article
Description
Abstract
In order to test the possible effect of chronic treatment with met-enkephalin upon the LHadenohypophyseal cells, an imrnunohistochemicalmorphometric study was carried out in rats of both sexes receiving a daily dose of 40 pg of met-enkephalin intramuscularly over 15 days. Following the administration of the opioid, a drastic decrease in the cellular, cytoplasmic and nuclear areas when compared to the normal and control animals was detected. Morphologically, the main finding in males was the appearance of irregularly-shaped pseudovacuolated cells. On the other hand, in females a decrease in the intensity of reaction was found. These results strongly suggest a decrease in the activity of the LH-adenohypophyseal cells following chronic administration of met-enkephalin.
publication.page.subject
LH , Adenohypophysis
Citation
URI
http://hdl.handle.net/10201/18484
item.page.embargo
Collections
Histology and histopathology Vol. 9, nº 2 (1994)
Ir a Estadísticas