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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Kuroda, Naoto | es |
dc.contributor.author | Jin, Y.L. | es |
dc.contributor.author | Hamauzu, T. | - |
dc.contributor.author | Toi, M. | - |
dc.contributor.author | Miyazaki, E. | - |
dc.contributor.author | Hiroi, Makoto | - |
dc.contributor.author | Moriki, T. | - |
dc.contributor.author | Enzan, H. | - |
dc.date.accessioned | 2011-06-30T12:00:33Z | - |
dc.date.available | 2011-06-30T12:00:33Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/22497 | - |
dc.description.abstract | To examine the distribution of CD34-positive and ASMA-positive stromal cells in various breast lesions, we performed immunohistochemical assays (using a streptavidin-biotin immunoperoxidase technique) of tissue specimens, obtained by excisional biopsy and partial or total mastectomy, from 62 patients with breast lesions. Specimens were obtained from 64 lesions as follows: fibrocystic disease (n=12), intraductal papilloma (n=4), fibroadenoma (n=17), invasive lobular carcinoma (n=6), invasive ductal carcinoma (n=20) and invasive micropapillary carcinoma (n=5). In normal breast tissue (controls), CD34-positive spindle cells were abundant in the intralobular stroma, but no ASMApositive stromal cells were identified except myoepithelial cells. Small to large numbers of CD34- positive cells were observed in the stroma of 29 of 33 benign diseases. In all invasive carcinomas (lobular, ductal and micropapillary), no CD34-positive stromal cells were observed in the stroma. In the stroma of benign lesions, the number of ASMA-positive stromal cells was various, but the stroma of all invasive breast cancers contained ASMA-positive stromal cells. The present results indicate that disappearance of CD34- positive stromal cells consistently occurs in the stroma of invasive carcinoma of the breast, irrespective of histological type and may be associated with the presence of ASMA-positive stromal cells. | es |
dc.format | application/pdf | es |
dc.format.extent | 6 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Immunohistochemistry | es |
dc.subject | Breast cancer | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina | es |
dc.title | Consistent lack of CD34-positive stromal cells in the stroma of malignant breast lesions | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol.20, nº 3 (2005) |
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Consistent lack of CD34positive stromal.pdf | 3 MB | Adobe PDF | Visualizar/Abrir |
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