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Título: | Primary B-cell gastric lymphomas of mucosaassociated lymphoid tissue. Histological and immunohistochemical study of ten cases on surgical specimens |
Fecha de publicación: | 1992 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Gastric malignant lymphoma Immunohistochemistry |
Resumen: | Ten cases of gastric mucosa-associated lymphoid-tissue B-cell lymphoma were studied on surgical specimens by histology and immunohistochemistry, with monoclonal and polyclonal antibodies for B- and T-cells. For the first time, percentage of centroblast-like cells was appreciated, using their LN1 positivity, by opposition to the negativity of centrocyte-like cells (LN2 immunoreactivity alone). Lymphomas were divided into four main groups: A) centrocyte-like cells; B) centrocyte-like cells and immunocytoma; C) centrocyte-like cells admixed to centroblast-like cells; and D) centrocyte-like cells, immunocytoma and at least 30% of centroblast-like cells. Group C was divided into 3 subgroups: C1 (rare centroblast-like cells); C2 (30-50% of centroblast-like cells); and C3 (predominant centroblast-like cells). Therefore low grade (A, B, Cl) and high grade malignancy groups (C2, C3, D) were identified: this preliminary subdivision could be extended in larger series and applied to mucosa-associated lymphoidtissue lymphoma from other sites. Furthermore, the possible prognostic significance of this subdivision could be evaluated by correlation with long term follow up. |
Autor/es principal/es: | Lavergne, Anne Kanavaros, Panagiotis Galian, Annie |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/18289 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 8 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 7, nº 1 (1992) |
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Primary Bcell gastric lymphomas of mucosaassociated.pdf | 396,68 kB | Adobe PDF | Visualizar/Abrir |
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