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http://hdl.handle.net/10201/17812
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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Facchetti, Fabio | es |
dc.contributor.author | Tardanico, Regina | es |
dc.contributor.author | Bonetti, Maria F. | - |
dc.contributor.author | Guerini, Agostino | - |
dc.contributor.author | Callea, Francesco | - |
dc.date.accessioned | 2011-01-17T12:39:06Z | - |
dc.date.available | 2011-01-17T12:39:06Z | - |
dc.date.issued | 1986 | - |
dc.identifier.issn | 0213-3911 | es |
dc.identifier.uri | http://hdl.handle.net/10201/17812 | - |
dc.description.abstract | The distribution pattern of HBsAg, HBcAg and Delta-Ag was investigated by immunohistochemistry in a series of paraffin embedded liver tissue specimens from 45 subjects with serum HBsAg and anti-Delta antibody positivity. An indirect immunoperoxidase technique was used. Stains for HBsAg, HBcAg and Delta-Ag were alternatively carried out on serial tissue sections and, for the first time, consecutively in a single section (triple immunostaining). Simultaneous presence of all antigens occurred in 7 out of 45 cases, and of two antigens (HBsAg and Delta-Ag) in the remaining 38. Two antigens (either HBsAg and HBcAg or HBcAg and Delta-Ag) could also be shown in the same cell. A series of new observations was forwarded by the successful application of triple immunostaining in the present series: 1) high frequence of simultaneous presence of HBcAg and Delta-Ag (7 out of 45 cases = 16%); 2) cytoplasmic localization of Delta-Ag; 3) localization of HBcAg on the cell membrane of HBsAg positive Ground- Glass (G-G) hepatocytes; 4) Ground-Glass appearance of hepatocytic cytoplasm associated with exclusive content of HBcAg (HBcAg-Ground-Glass: a new variant of G-G-hepatocytes). | - |
dc.format | application/pdf | es |
dc.format.extent | 5 | es |
dc.language | eng | es |
dc.publisher | Murcia : F. Hernández | es |
dc.relation.ispartof | Histology and histopathology | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | Viral hepatitis | es |
dc.subject | Immunohistochemistry | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología | es |
dc.title | HBsAg, HBcAg and Delta-Ag in liver tissue: simultaneous visualization in a single tissue section by triple immunostaining | es |
dc.type | info:eu-repo/semantics/article | es |
Aparece en las colecciones: | Vol. 1, nº 2 (1986) |
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Fichero | Descripción | Tamaño | Formato | |
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HBsAg HBcAg and DeltaAg in liver tissue simultaneous visualization in a single tissue section by triple immunostaining1.pdf | 334,64 kB | Adobe PDF | ![]() Visualizar/Abrir |
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