Histology and histopathology Vol. 3, nº 1 (1988)

Ir a Estadísticas

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    lmmunocytochemical localization of parathyroid hormone in rabbit parathyroid glands
    (Murcia : F. Hernández, 1988) Shizuko Shoumura; Noriko Ishizaki; Shoichi Emura; Yuji Iwasaki; Tomo Yamahira; Hideo Isono
    Immunocytochemical localization of parathyroid hormone was examined in the rabbit parathyroid gland by means of protein A-gold technique. Protein A-gold particles were observed on the secretory granules and the large secretory granules thought to be storage granules. No protein A-gold particles were observed on cisternae of the endoplasmic reticulum and the Golgi apparatus
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    Ultrastructural computerized morphometry of platelets in chronic myelogenous leukemia making use of ultra-thin sections and freeze-fracture procedure a preliminary approach
    (Murcia : F. Hernández, 1988) Bianciardi, G.; Battistelli, S.; Toti, P.; Vallesi, G.; Weber, G.
    Biochemical and morphological data have shown that the circulating platelets are deeply altered in patients with chronic mielogenous leukemia. In this report we describe the results of ultrastructural morphometry performed by means of a computerized device of the platelet shape (ultra-thin sectioned platelets) and of the platelet plasma-membrane (freezefractured platelets). Platelets appeared deeply modified: reduced mean platelet area and perimeter, increased surface density of the openings of the surface connected canalicular system, abnormal features of the platelet cytoplasm and some aspects of platelets joined together even if with heterogeneity in these findings did appear from patient to patient.
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    Ultrastructural pathologic changes of rat extraembryonic visceral endodermal cells exposed to teratogenic antibodies in vivo
    (Murcia : F. Hernández, 1988) Leung, C.C.K.; DeSha, D.L.; Bui, L.; Cheewatrakoolpong, B.
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    Distribution of ferric iron in larval lampreys, Petromyzon marinus L
    (Murcia : F. Hernández, 1988) Hall, S.J.; Youson, J.H.
    The distribution and abundance of ferric iron in larval lampreys (Petromyzon marinus L.) were investigated using light microscopy and the Prussian blue stain. Animals from various watersheds contained different concentrations of iron, although the sites of deposition were the same for all animals. A major portion of iron is within adipose tissue. while the liver, and cartilage contain predominantly low to trace amounts of iron. respectively. Iron is associated with fibrous connective tissue in several places in the body, and this association may have particular significance in the inner ear. Iron is also located in cells of the meninges. The presence of iron in the epithelia1 cells of the posterior intestine may reflect elimination of the metal through the extrusion of iron-loaded cells into the intestinal lumen. Iron within mucous cells of the epidermis, suggest elimination of iron during mucous secretion. Iron-loaded cells of bipolar shape are also present in the epidermis, but are particularly prominent around the branchiopore. Low concentrations of iron are observed within in melanin-containing macrophages (melano-macrophages) in regions of iron absorption, erythrophagocytosis, and haemopoiesis. High levels of iron in the epithelia and lumina of pronephric tubules are concomitant with degeneration of this organ. These data are evidence of the wide spread distribution of iron in lamprey tissues and additional evidence for the potential value of lampreys for the study of iron metabolism in vertebrates.
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    Neuron specific enolase-positive breast carcinomas
    (Murcia : F. Hernández, 1988) Erikstein, Bjerrn; Nesland, Jahn M.; Ottestad, Lars; Lund, Eiliv; Johannessen, Jan Vicents
    Ninety-eight patients treated for breast carcinomas were followed from 54 to 75 months after primary diagnosis. All had undergone a modified radical mastectomy with removal of axillary lymph nodes. 36 breast carcinomas were NSE-positive and 62 were negative. NSE-positive tumours were significantly more frequently estrogen receptor-positive than the NSEnegative tumours, and the estrogen receptor values were higher in the NSE-positive groups. Patients with NSE-positive tumours and patients with NSE-negative tumours did not differ with regard to presence of lymph node metastases at the time of primary surgery. However, the study showed that patients with NSE-positive tumours had a tendency towards more lymph node metastases after primary surgical intervention, but a better outcome than patients with NSE-negative tumours and metastases. This study, with a 5-year follow up, failed to demonstrate any major prognostic significance of immunostaining for NSE.