Browsing by Subject "Hypereosinophilic syndrome"
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- PublicationOpen AccessAssociation of sinus histiocytosis with massive lymphadenopathy and idiopathic hypereosinophilic syndrome(Murcia : F. Hernández, 1987) Hernández, Dimas; Gutierrez, Luis; Duque, Herminia; Olavarria, Renato; Muci, Rafael; Wunaii, HermanA patient was evaluated because of edema, pruritus and generalized painless lymphadenopathy. Laboratory tests showed marked eosinophilia without known etiology. CT scan of abdomen revealed multiple lymph nodes in retroperitoneal area. Lymph node biopsy was reported as sinus histiocytosis, bone marrow biopsy showed hipercellularity with marked infiltration of normal eosinophils. During his admission he developed Coombs positive hemolytic anaemia. Once he was stable, a laparotomy was performed and the patient died two days later because of septic shock. Autopsy revealed sinus histiocytosis with massive lymphadenopathy (SHML) with extranodal involvement of duodenum, spleen and prostate; septic liver and spleen, pyelonephritis, marked infiltration of eosinophilis in lymph nodes, spleen, liver duodenum and lungs. To the best of our knowledge, this is the first case report of the association of SHML and Idiopathic Hypereosinophilic Sundrome (HES) .