Investigación

Permanent URI for this community

https://hdl.handle.net/10201/51

Investigación contiene los documentos generados por los docentes e investigadores de la Universidad en su labor de investigación. Este depósito tiene como objetivos el almacenamiento, la gestión, la preservación y la difusión de estos documentos, y pretende contribuir al aumento de la visibilidad del trabajo desarrollado por los miembros de la comunidad universitaria.

Browse

Filter results by year or month

Now showing 1 - 20 of 19785

Restricted
Head-tracking as an interface device for image control in digital pathology: a comparative study.
(0001-01-20) Alcaraz-Mateos, Eduardo; Turic, Iva; Nieto-Olivares, Andrés; Pérez-Ramos, Miguel; Poblet, Enrique; Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica
Inasmuch as the conventional mouse is not an ideal input device for digital pathology, the aim of this study was to evaluate alternative systems with the goal of identifying a natural user interface (NUI) for controlling whole slide images (WSI).
Open Access
#FNAFriday: How cytopathologists learn, teach, and share knowledge on Twitter.
(0001-01-20) Expósito-Afonso, Idaira J; Alcaraz-Mateos, Eduardo; Labiano, Tania; Pijuan, Lara; Temprana-Salvador, Jordi; Fitzhugh, Valerie; Fuller, Maren; Madrigal, Emilio; Walavalkar, Vighnesh; Baloch, Zubair W; Jiang, Xiaoyin Sara; Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica
Twitter is an expanding social media network among cytopathologists to share knowledge. Tweets are made up of text which may also include images or video. All tweets labeled under a hashtag can be tracked. The #FNAFriday hashtag was created in 2015 by one of the authors (X.J.) to build a community of individuals, to educate and share interesting cases, and highlight a variety of diagnoses with FNA specimens.
Restricted
Comparison of muscle activity while using different input devices in digital pathology.
(0001-01-22) Alcaraz-Mateos, Eduardo; Hernández-Gómez, Rubén; Rojas Calvente, Estefanía; Sánchez-Campoy, Nicolás; Martínez González-Moro, Ignacio; Caballero-Alemán, Fuensanta; Poblet, Enrique; Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica
The high prevalence of musculoskeletal disorders in pathologists, together with the current trend towards the digitization of pathology, prompted us to study the different types of input devices employed during the revision of whole slide images, in order to investigate the pattern and extent of muscle activity involved in their use.
Open Access
Chronic follicular pancreatitis: a space occupying lesion with spontaneous resolution.
(0001-01-24) Sánchez Navarro, Elena; López Martín, Aurelio; Alcaraz Mateos, Eduardo; Molina Muñoz, José Manuel; Egio Ros, Marta; Morales López, Germán; Pérez-Cuadrado Martínez, Enrique; Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica
Follicular pancreatitis (FP) is an extremely odd entity characterized by the presence of a pseudotumor that histologically presents lymphoid aggregates and germinal centers. The authors present the case of a 67-year-old woman with epigastric pain and jaundice. Endoscopic ultrasonography (EUS) was performed, revealing a 14x15 mm hypoechoic area with irregular edges in the head of the pancreas. The in situ cytological study showed polymorphic lymphoid cellularity, without atypia suggesting neoplasia. The cell block and the immunohistochemical study showed a polyclonal population with a pattern suggestive of FP. The patient presented spontaneous clinical improvement. The EUS follow up three months later shown pancreatic parenchyma with homogeneous echogenicity and no space occupying lesions were indentified. Since the diagnosis of FP has been reached after surgery in most cases, the treatment is not well established. However, no recurrences have been reported after surgery and spontaneous resolution has been observed in incomplete resections, which suggests the indication for conservative management. Diagnostic EUS has a fundamental role in the differential diagnosis between FP and pancreatic neoplasms, two entities with very different prognosis, and makes it possible to avoid, in the case of FP, unnecessary surgeries with the associated morbidity and mortality.
Open Access
How do cytopathologists learn fine needle aspiration techniques? An international survey.
(0001-01-25) Alcaraz-Mateos, Eduardo; Exposito-Afonso, Idaira Jael; Labiano-Miravalles, Tania; Pijuan, Lara; Temprana-Salvador, Jordi; Zhao, Qing; Jiang, Xiaoyin Sara; Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica
Fine needle aspiration cytology (FNAC) is a widely accepted diagnostic technique, but performance varies according to expertise. Little is known about variation in FNAC training practices worldwide. We surveyed pathologists using social media networks to determine FNAC training practices internationally.
Open Access
Satiety hormone secretion induced by a carob-based formulation (Csat®) after simulated gastrointestinal digestion and colonic fermentation in STC-1 cells
(Elsevier, 0001-07-26) Benito-Vázquez, Iván; Rosell, María de los Ángeles; Lates-Profir, Natalia; Díez Municio, Marina; Moreno, Francisco Javier; Frontela Saseta, María del Carmen; López Nicolás, Rubén; Tecnología de Alimentos, Nutrición y Bromatología
Csat® is a carob-derived based product standardized in galactomannans, inositols, and gallic acid, with potential applications in weight management and metabolic health. This study evaluated the effects of Csat® on satietyrelated enteroendocrine signalling after simulated gastrointestinal digestion and colonic fermentation. A standardized INFOGEST in vitro digestion model was combined with batch colonic fermentation using human faecal inoculum, and the resulting fractions were tested in STC-1 cells to quantify glucagon-like peptide-1 (GLP-1) and cholecystokinin (CCK) secretion. Digestive stability of key bioactive compounds was assessed by HPLC-MS. Undigested Csat® did not stimulate hormone secretion, whereas gastric digestion induced the strongest enteroendocrine response, significantly increasing both GLP-1 and CCK release. The intestinal soluble phase maintained a moderate stimulatory effect. During colonic fermentation, galactomannans were extensively degraded, while pinitol remained stable and gallic acid showed variable recovery. Fermentation kinetics revealed active microbial metabolism, with early fermentation associated with the highest endocrine response. GLP-1 and CCK secretion peaked at 4 h fermentation and progressively declined at later stages. Overall, Csat® showed a marked phase-dependent endocrine activity, with gastrointestinal processing and early microbial fermentation generating the most bioactive fractions. These findings support the potential of Csat® to modulate satiety-related pathways through coordinated digestion- and microbiota-derived mechanisms.
Open Access
Ángela García Codoñer. Arte feminista en la primera mitad de los años 70 en España
(Diputació de València, 0006-01-21) Isabel Tejeda Martin; Isabel Tejeda Martin; Bellas Artes; Facultades de la UMU::Facultad de Bellas Artes
The book Ángela García Codoñer offers a comprehensive overview of the Spanish artist’s life and work, highlighting her role in feminist and pop-influenced art from the 1970s onward. It situates García Codoñer’s practice within broader debates about gender, representation, and artistic experimentation, tracing her evolution from early collage and acrylic series that deconstruct traditional portrayals of women to more abstract, color-driven compositions. Essays contextualize her contributions within Spanish contemporary art and discuss her academic career and influence as a professor and researcher. The publication also documents key works and series, emphasizing her sustained engagement with form, identity, and social critique.
Open Access
Folate fortification of white and whole-grain bread by adding Swiss chard and spinach. Acceptability by consumers
(Elsevier, 0016-05-14) López Nicolás, Rubén; Frontela Saseta, María del Carmen; González-Abellán, Raquel; Barado-Piqueras, Ana; Perez-Conesa, Darío; Ros Berruezo, Gaspar; Tecnología de Alimentos, Nutrición y Bromatología
The aim of this work was to study the effect of bread-making on the content of endogenous folate of white and whole-grain bread fortified with either Swiss chard or spinach at 20 g/100 g and 40 g/100 g measured by HPLC (H4-folate and 5-CH3-H4-folate); and to assess the sensory acceptability of folatefortified breads compared to non-fortified breads. The fortification of breads with 20 g/100 g and 40 g/100 g vegetables significantly (p < 0.001) increased the total folate content (from 19.9 to 57.9 mg/ 100 g in white bread and from 37.4 to 75.5 mg/100 g in whole-grain bread). Moreover, 40 g/100 g Swiss chard- and spinach-fortified breads obtained higher scores in overall acceptability than 20 g/100 g fortified or control bread for both white and whole-grain breads. The consumption of two servings (56 g each) per day of 40 g/100 g fortified bread would meet the daily folate requirements by 14.3e21.8% in adults and 9.6e14.5% in some special states like women of child-bearing age.
Open Access
Carte de Visite Retrato femenino
(1870) Anónimo; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato femenino
(1875) Clément; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato masculino
(1875) Sandels, Carl; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato infantil post mortem
(1880) Ricard, F.; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato masculino
(1885) Leinenveber, Georg; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato femenino
(1885) Stephanie; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato familiar
(1890) Kremer, Gebr.; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato masculino
(1890) Fischer, F.; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato masculino
(1895) Sonntag, Wilhelm; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato infantil
(1895) Caillot, J.; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato masculino
(1895) Schneider, M.; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)
Open Access
Carte de Visite Retrato femenino
(1895) Perret, B.; Historia del Arte; Laboratorio de Investigación Fotográfica de la Universidad de Murcia (Lifum)