DigitalUM :: Browsing by browse.metadata.contributordepartment "Dermatología, Estomatología, Radiología y Medicina Física"

Browsing by browse.metadata.contributordepartment "Dermatología, Estomatología, Radiología y Medicina Física"

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Open Access
A comparison of the shear bond strength of a resin cement and two orthodontic resin adhesive systems
(E.H Angle Education and Research, Inc., 2005-01-01) Vicente, Ascensión; Bravo, Luis Alberto; Romero Maroto, Martín; Ortiz Ruiz, Antonio José; Canteras Jordana, Manuel; Dermatología, Estomatología, Radiología y Medicina Física
The object of this study was to compare the shear bond strength and the quantity of adhesive remaining on the tooth after the debonding of brackets bonded with two light-cured orthodontic resin adhesive systems (Transbond XT and Light-Bond) and a dual-cured resin cement (RelyX Unicem). Seventy-five premolars were divided into three groups. In each group, brackets were bonded with one of the adhesives according to the manufacturer's instructions. Shear bond strength was measured using a universal test machine at a crosshead speed of one mm/min, and adhesive remnant was quantified using image analysis equipment. Our results showed that the resin cement produced significantly lower bond strength than the two orthodontic resin adhesive systems. It was also observed that the bond strength produced by Light-Bond was significantly greater than that of Transbond XT. RelyX left significantly less remnant adhesive than Transbond XT and Light-Bond. Between the two orthodontic systems, Light-Bond left significantly less adhesive on the tooth than Transbond XT.
Open Access
A new management technique for symptomatic haematomas following therapeutic vacuum-assisted biopsy.
(MDPI, 2019-09-19) Guzman Aroca, Florentina; Berná Serna, Juan de Dios; Garcia Ortega, Ana Azahara; Hernández Gómez, Dolores; Berná Mestre, Juan de Dios; Dermatología, Estomatología, Radiología y Medicina Física
The aim of this study was to investigate the efficacy of the vacuum-assisted biopsy (VAB) system in evacuating symptomatic haematomas after VAB excision of benign breast lesions. We retrospectively analysed the data of eight patients with symptomatic and large haematomas who were treated with VAB evacuation between 10 and 14 days after VAB excision. Only one case underwent the procedure 24 h after VAB excision, due to the patient reporting intense pain, which was relieved after application of the technique, even though it had to be done twice. This new clinical application of the VAB system for evacuating symptomatic breast haematomas was successful in all the cases in the present study. No technique-related complications were observed. Conclusions: To the best of our knowledge, this is the first study to reveal that VAB evacuation of symptomatic haematomas is safe, effective, quick and well-tolerated by patients.
Open Access
A new use for self-etching resin adhesives: Cementing bone fragments
(Elsevier, 2010-06-18) Ortiz Ruiz, Antonio José; Vicente Hernández, Ascensión; Camacho Alonso, Fabio; López Jornet, P.; Dermatología, Estomatología, Radiología y Medicina Física
Objectives: To evaluate the bond capacities of four self-etching resin cements and the self-etching adhesives of the same manufacturer when used to cement bone fragments and compare them with a well-known N-butyl-2-cyanoacrylate bone adhesive. Methods: 125 cylindrical bone specimens from pig mandibular ramus bone were prepared using terphane burs and cemented to the corticals of 125 other specimens obtained from pig mandibular body bone using the following bond systems: Group A: Adper PLP/Relyx; group B: Optibond/Maxcem; group C: Hystoacryl; group D: AdheSE/Multilink; group E: G-Bond/G-Cem. Shear bond strength was measured 15 min after cement application using a universal testing machine. Results: Shear bond strength results: group A 2.54 ± 0.23 MPa; group B 4.83 ± 0.4 MPa; group C 2.90 ± 0.24 MPa; group D 2.10 ± 0.17 MPa; group E 4.22 ± 0.24 MPa. Values for shear bond strength were significantly greater for group B and E compared to groups A, C and D (p < 0.005, test Mann–Whitney). SEM images showed the presence of a hybrid layer similar to that formed by these bond systems when used on dentine. Conclusion: Within the limitations of an in vitro investigation, results show that self-etching resin cements together with self-etching adhesives may be used for cementing bone fragments.
Embargo
A surgical approach to root coverage and correction of mucogingival conditions and deformities in mandibular incisors with isolated gingival recession: free mucogingival graft. A pilot prospective cohort study
(Quintessence Publishing Co Inc, 2024-03-20) Moreno Rodríguez, José Antonio; Ortiz Ruiz, Antonio José; Dermatología, Estomatología, Radiología y Medicina Física
The aim of this study was to present a periodontal plastic surgery approach to treat gingival recessions (GRs) and correct mandibular incisor mucogingival conditions and deformities. Isolated deep GRs (≥ 3 mm) in the mandibular incisors (n = 24 teeth) were treated: 66.6% of sites were recession types 2 or 3, and 58.3% of teeth were malpositioned. Recessions were treated using free mucogingival grafts (FMGs) harvested from the buccal aspect of donor teeth with altered passive eruption or healthy periodontal support, with < 3 mm between the cementoenamel junction and the buccal alveolar crest. Clinical parameters (GR, clinical attachment level, interproximal papilla tip location, keratinized tissue, vestibule depth) and root coverage esthetic score were evaluated at 9 months. FMG significantly reduced GR (P < .001) and increased keratinized tissue (P < .001) without loss of vestibule depth (P > .05). Mean root coverage was 94.37% ± 10.60%, mean residual GR was 0.08 ± 0.65 mm, and the mean root coverage esthetic score was 8.9 ± 1.24. Recession types 2/3 showed significant interproximal clinical attachment gain (P < .05). The interproximal papilla was significantly augmented at sites with papilla loss (P < .001). No clinical attachment loss (P = .346) was detected at donor sites. These results suggest that FMG is a promising root coverage approach for recession types 1, 2, and 3, correcting mucogingival conditions and deformities and reconstructing the interproximal papilla.
Embargo
Acoustic radiation force impulse imaging for evaluation of the thyroid gland
(Wiley, 2014-06-01) Cepero Calvete, Ángela; Berná Mestre, Juan de Dios; Rodriguez Gonzalez, José Manuel; Sáez Martinez, Elena; Torregrosa Sala, Begoña; Rios Zambudio, Antonio; Dermatología, Estomatología, Radiología y Medicina Física
To study acoustic radiation force impulse (ARFI) imaging as a new quantitative and noninvasive tool for evaluating thyroid nodules and to compare ARFI imaging with other tools for studying thyroid nodules: sonography, real-time elastography, and fine-needle aspiration biopsy. We conducted a prospective study from June 2011 to June 2012, which analyzed 157 thyroid nodules (129 benign and 28 malignant) using the ARFI technique and a 9-MHz probe. Shear wave velocities (SWVs) were obtained while the patients held their breath to avoid respiratory movement artifacts. All nodules underwent conventional sonography and real-time elastography of the thyroid gland. All patients received either a cytologic examination using fine-needle aspiration biopsy or a histologic examination from thyroid surgery to verify the diagnosis (reference standard). The mean SWV ± SD on ARFI imaging in healthy, nodule-free thyroid glands was 2.04 ± 0.51 m/s (range, 0.76–3.63 m/s). The mean SWV in benign thyroid nodules was 1.70 ± 0.55 m/s (range, 0.50–2.80 m/s), and the mean SWV in malignant nodules was 3.39 ± 1.15 m/s (range, 1.50–6.08 m/s). When we used an SWV greater than 2.50 m/s for the diagnosis of malignant nodules and less than 2.50 m/s for the diagnosis of benign nodules, the sensitivity and specificity of ARFI imaging were 85.7% and 96.0%, respectively. We found that SWVs were substantially higher in malignant nodules than benign ones. Perhaps if ARFI imaging is used in conjunction with sonographic findings and patient demographics, it will be possible to find a combination of factors that would yield a negative predictive value high enough to distinguish benign from malignant nodules with confidence, which may lead to a decrease in the biopsy rate for benign nodules.
Embargo
Adhesion promoters: effects on the bond strength of brackets
(Mosher & Linder, Inc., 2005-12-01) Vicente Hernández, Ascensión; Bravo González, Luis Alberto; Romero Maroto, Martín; Ortiz Ruiz, Antonio José; Canteras Jordana, Manuel; Dermatología, Estomatología, Radiología y Medicina Física
Purpose To evaluate the effect of two adhesion promoters on shear bond strength and remnant adhesive of brackets cemented with a light-cured orthodontic adhesive resin system. Methods The two adhesion promoters tested were OrthoSolo and All-Bond 2 Primer. Seventy-five upper premolars were divided into three groups of 25. A control group was established using Transbond-XT adhesive system and two experimental groups: Transbond-XT/OrthoSolo and Transbond-XT/All-Bond 2. Shear bond strength was measured using a universal testing machine and adhesive remnant was quantified using an image analysis equipment. Results The application of Orthosolo significantly increased bond strength for Transbond-XT adhesive system (P< 0.017). All-Bond 2 primer did not significantly increase the bond strength of Transbond-XT (P> 0.017). The Adhesive Remnant Index results and the analysis of the percentage of area of tooth occupied by adhesive indicated that adhesive remnant after debonding did not increase significantly (P> 0.05) with the use of either of the promoters.
Embargo
Aesthetic outcomes of different materials for delayed, single-tooth restorations for immediately placed implants. A randomized controlled clinical trial
(Elsevier, 2024-07) Pardo Zamora, Guillermo; Molina-González, Juan Manuel; Martínez Marco, José Francisco; Ortiz Ruiz, Antonio José; Mardas, Nikos; García-Sánchez, Rubén; Dermatología, Estomatología, Radiología y Medicina Física; Clínica Odontológica Integrada Infantil
Objectives The aim of this study is to compare the aesthetic outcomes of metal porcelain (C), lithium disilicate (T1) and porcelain-layered zirconium (T2) immediate implant-supported single crowns in the anterior maxilla. Materials and methods Forty-five immediate dental implants were provided for 45 patients that required the extraction of a single tooth in the anterior maxilla. A temporary prosthesis was provided at 8 weeks after placement followed by the final prosthesis at 24 weeks post-implantation. The patients were randomly allocated into 3 groups: 15 patients in the control group (C) received a metal-porcelain restoration, 15 patients (T1) received a lithium disilicate (LD) restoration and 15 patients (T2) received a porcelain-layered, zirconium (Z) restoration. Pink (PES) and White (WES) esthetic scores, radiographic bone levels, periodontal parameters and patient's esthetic satisfaction using a visual analogue scale (VAS) were evaluated at the time of final restoration placement (t0) and at 12-months post-loading (t12). Results No implants were lost during the duration of this study. Statistically significant higher WES and VAS scores (p < 0.05) were recorded in T1 vs C and T1 vs T2 groups respectively. Similar radiographic bone levels and periodontal parameters were recorded in all groups. Conclusion Within the limitations of this study, it was concluded that T1 restorations provided better WES outcomes when compared to C restorations and better VAS scores when compared to T2 restorations at 12 months post-loading. Besides, different material interphases did not have an impact in PES, bone levels or periodontal parameters. Clinical relevance There is limited data comparing aesthetic outcomes of implant supported single crowns made of different ceramic materials based on accepted and comparable indexes and the evaluation of the patient's perspective regarding these aesthetic outcomes.
Open Access
An adverse effect of Ocrelizumab treatment in a patient with multiple sclerosis: a case report of necrotizing periodontitis
(Gavin Publishers, 2023-04-04) Montoya-Carralero, José María; Sánchez-Pérez, Arturo; Jornet-García, Alfonso; Moya Villaescusa, María José; Dermatología, Estomatología, Radiología y Medicina Física
Multiple Sclerosis (MS) and Necrotizing Periodontitis (NP) are two diseases whose aetiologies and pathophysiologies do not appear to have a common link; however, treating MS with monoclonal antibodies and the decrease in humoral immunity that this entails can be a trigger or an aggravation in patients who present with quiescent NP. We describe a clinical case of NP, including clinical manifestations, treatment, and evolution during therapy with ocrelizumab and to review risk factors. A rapid progression of NP was evidenced. During the patient’s evolution, she suffered bilateral pneumonia due to coronavirus disease 2019, requiring treatment with corticosteroids and antibiotics, which led to clinical relief of her NP. Based on this case, we believe that regulated dental monitoring of patients with MS before, during, and after the administration of monoclonal antibodies may help prevent periodontal deterioration.
Embargo
An experimental study of bisphosphonate-induced jaws osteonecrosis in Sprague–Dawley rats
(Wiley, 2010-10-01) López Jornet, María Pía; Camacho Alonso, Fabio; Molina Miñano, Francisco; Gómez García, Francisco; Vicente Ortega, Vicente; Dermatología, Estomatología, Radiología y Medicina Física
Objective: Patients undergoing treatment with bisphosphonates may develop jaw lesions consisting mainly of bone necrosis. The present study describes a model of maxillary osteonecrosis in Sprague–Dawley rats, applying bisphosphonates and examines the changes occurring after tooth extraction. Material and methods: A total 200 animals were included in a randomized prospective study involving the following groups: group I (control, 20 rats without drug treatment), group II (60 animals administered dexamethasone 1 mg/kg/day for 7, 14 and 21 days, in subgroups of 20 animals each), group III (60 animals administered pamidronate daily at a dose of 3 mg/kg) and group IV (60 animals administered pamidronate and dexamethasone). In all groups, molar extraction was carried out on the right upper maxillary or mandibular side 8, 15 and 22 days after the start of dosing. The rats were killed 14 and 28 days after extraction in all groups. Results: A total of 18 cases of osteonecrosis were recorded in the group administered pamidronate and dexamethasone. Osteonecrosis affected the upper maxilla in 10 cases and the mandible in eight cases, and was circumscribed to the extraction zone in all cases. Osteonecrosis was not seen in any of the other groups. Conclusions: The administration of pamidronate and dexamethasone in rats subjected to molar extraction increases the risk of osteonecrosis.
Open Access
An objective and subjective evaluation of masticatory efficiency in periodontal patients before and after basic periodontal therapy: a case series study
(MDPI, 2025-04-12) Moya Villaescusa, María José; López-Lisón, Claudia; Montoya-Carralero, José María; Jornet García, Alfonso; Sánchez Pérez, Arturo; Dermatología, Estomatología, Radiología y Medicina Física
Abstract: Background: Periodontal disease is a multifactorial infectious pathology that affects dental supporting tissues, impacting the health and quality of life of patients. Assessing chewing efficiency before and after periodontal therapy is crucial to better understand its impact on the quality of life of periodontal patients. Thus, the aim of this case series study was to determine whether basic periodontal therapy improves masticatory ability and efficiency in patients with mild to moderate periodontitis. Methods: A prospective, longitudinal, case series study was carried out in 42 periodontal patients treated at the University Odontology Clinic. Masticatory efficiency before and after basic periodontal treatment was assessed using both objective (HueCheck Gum test) and subjective (Quality of Masticatory Function Questionnaire: QMFQ) methods. Results: Significant improvements (p = 0.0001) were observed in periodontal variables such as hygiene index (HI), probing depth (PD), and clinical attachment level (CAL), as well as in the initial and final QMFQ total score (p = 0.045). In addition, significant differences were found in posttreatment QMFQ scores related to parafunctional habits (p = 0.046) and facial patterns, especially in meat consumption (p = 0.042) fruit and vegetable consumption (p = 0.007, p = 0.044). The initial mean HueCheck Gum test values were 0.59 ± 0.09 and the final values were 0.61 ± 0.11. These differences were not statistically significant. Conclusions: Basic periodontal treatment does not objectively improve the masticatory efficiency of patients with mild–moderate periodontitis, evaluated by means of the test of mixing two chewing gums, but it does offer subjective improvements.
Open Access
Analysis of the porosity and microhardness of glass ionomer cements
(Kaunas University of Technology (Lithuania), 2022-02-18) Cabello Malagón, Inmaculada; Cánovas Hernández, Basilio; Martínez Hernández, Elisa; Serna Muñoz, Clara; Pérez Silva, Amparo; Ortiz Ruiz, Antonio José; Dermatología, Estomatología, Radiología y Medicina Física
Glass ionomer cements (GICs) are currently the first-choice materials in minimally invasive dentistry and are widely used in paediatric dentistry. The objective of this study was to evaluate the influence of viscosity and mixing on porosity and the relationship between the porosity and microhardness of GICs. Nine GICs were used: EQUIA® Forte Fil, Ionostar®Plus, 3MTMKetacTM Universal AplicapTM, Riva Light Cure HV®, Riva Silver®, Riva Protect®, VitremerTM, VitrebondTM Plus and Activa BioActive RestorativeTM. Samples were prepared from each material and images were obtained by scanning electron microscopy (SEM). Using software, the number and diameter of pores, area, and percentage of area they occupied were measured. After SEM analysis, the samples were used to make surface microhardness (SMH) measurements. Ionostar® Plus, EQUIA® Forte Fil and Riva Light Cure HV® had the highest number of pores. Riva Protect® had the largest pores and the highest percentage of pore-occupied area, while Activa BioActive RestorativeTM and VitrebondTM Plus had a smaller pore size and a smaller percentage by area. Riva Silver® and EQUIA® Forte Fil showed the highest microhardness values and VitrebondTM Plus and VitremerTM the lowest. In conclusion, when the cement viscosity is low, the type of mixture determines the degree of porosity, but has less influence when viscosity is high. There was no correlation between microhardness and the porosity of GICs.
Embargo
Anestésicos locales dentales: ansiedad y reactividad cardiovascular
(Ediciones Avances, S.L., 2001-09) Chiva García, Fernando; Báguena Gómez, Juan Carlos; Serrano Belda, Manuel; Vilaplana Gómez, Juan Angel; Ortiz Ruiz, Antonio José; Dermatología, Estomatología, Radiología y Medicina Física
Open Access
Apical approach in periodontal reconstructive surgery with enamel matrix derivate and enamel matrix derivate plus bone substitutes: a randomized, controlled clinical trial
(Springer, 2021-11-17) Moreno Rodríguez, José Antonio; Ortiz Ruiz, Antonio José; Dermatología, Estomatología, Radiología y Medicina Física
Objectives This parallel, randomized controlled clinical trial evaluated the influence of bone substitutes (BS) on the efficacy of the non-incised papillae surgical approach (NIPSA) with enamel matrix derivate (EMD) in resolving deep, isolated, combined non-contained intrabony and supra-alveolar periodontal defects, preserving the soft tissue. Material and methods Twenty-four patients were randomized to treatment with NIPSA and EMD or NIPSA plus EMD and BS. Bleeding on probing (BoP), interproximal clinical attachment level (CAL), interproximal probing depth (PD), recession (REC), location of the tip of the papilla (TP), and width of the keratinized tissue (KT) were evaluated before surgery and at 1 year post-surgery (primary outcomes). Wound closure was assessed at 1 week post‐surgery, and supra‐alveolar attachment gain (SUPRA-AG) was recorded at 1 year post‐surgery. Results At 1 week, 87.5% of cases registered complete wound closure and there were no cases of necrosis, without differences between groups (p > .05). At 1 year, all cases showed negative BoP. A significant PD reduction (NIPSA + EMD 8.25 ± 2.70 mm vs. NIPSA + EMD + BS 6.83 ± 0.81 mm) and CAL gain (NIPSA + EMD 8.33 ± 2.74 mm vs. NIPSA + EMD + BS 7.08 ± 2.68 mm) were observed (p < .001) in both groups, without significant between-group differences (p > .05). The residual PD was < 5 mm in all defects (NIPSA + EMD 2.50 ± 0.67 mm vs. NIPSA + EMD + BS 2.67 ± 0.78 mm). Soft tissues were preserved without significant between-group differences (REC: NIPSA + EMD 0.25 ± 0.45 mm vs. NIPSA + EMD + BS 0.17 ± 0.58 mm, p > .05; KT: 0.00 ± 0.43 mm vs. 0.08 ± 0.67 mm, p > .05). There were improvements in the papilla in both groups (TP: NIPSA + EMD 0.33 ± 0.49 mm vs. NIPSA + EMD + BS 0.45 ± 0.52 mm, p > .05), which was only significant in the NIPSA EMD + BS group (0.45 ± 0.52 mm; p < .05). In both groups, CAL gain was recorded in the supra-alveolar component, showing full resolution of the intrabony component of the defect in all cases (SUPRA-AG: NIPSA + EMD 1.83 ± 1.11 mm vs. NIPSA + EMD + BS 2.00 ± 1.76 mm, p > .05). Conclusions NIPSA and EMD with or without BS seem to be a valid surgical approach in the treatment of isolated, deep non-contained periodontal defects. In our study, both treatments resulted in significant PD reduction and CAL gain, that extended in the supra-alveolar component, without differences with the use of BS. Both treatments resulted in soft tissue preservation. However, the addition of BS may improve interdental papillary tissue. Clinical relevance NIPSA, with or without bone substitutes, resulted in significant periodontal improvement, with soft tissue preservation in isolated, deep non-contained periodontal defects. The application of bone substitutes may provide interproximal soft tissue gain.
Open Access
Apical approach to the treatment of peri-implantitis in the esthetic zone: nonincised papillae surgical approach (NIPSA). Case reports
(Quintessence Publishing Co, 2022-05-25) Rodríguez Moreno, José Antonio; Ruiz Ortiz, Antonio José; Dermatología, Estomatología, Radiología y Medicina Física
Objective: Advanced peri-impiantitis treatment is a ciinicai challenge. Reconstructive surgery is not suggested in defects with limited bony walls and/or in those with a suprabony defect. All studies of peri-implantitis reconstructive surgery have considered a marginal surgical approach. However, in the present case report, a new apical approach is presented for the reconstruction of an advanced peri-implantitis lesion. Materials and method: First, a non-surgical phase combines prosthetic, mechanical, and chemical strategies. Second, a surgical phase combines the apical nonincised papillae surgical approach (NIPSA) with biomaterials and a connective tissue graft. Conclusion: Successful results have been obtained when using a NIPSA for the treatment of peri-implantitis, despite the unfavorable characteristics of the peri-implant defect.
Embargo
Aplicación del ABP como metodología docente activa en urgencias odontológicas
(Diego Marín, 2013) Camacho Alonso, Fabio; Cascales peñalver, Francisco Javier; Sánchez Siles, Mariano; Dermatología, Estomatología, Radiología y Medicina Física
Embargo
Application of International Caries Detection and Assessment System (ICDAS) and Caries Management by Risk Assessment (CAMBRA) systems in child cancer patients: a clinical case report
(Springer, 2017-05-13) Hernández Fernández, Ana; Oñate Sánchez, Ricardo Elías; Fernández Miñano, Esther; Iniesta López Mantecio, P.; Ortiz Ruiz, Antonio José; Dermatología, Estomatología, Radiología y Medicina Física
Background Leukaemia represents 30–40% of all paediatric malignant tumours and is the main cause of death in patients aged <15 years. One of the main complications in these patients is infection, which may often occur in the oral cavity. Chemotherapy-related oral health problems may be reduced by oral healthcare strategies based on the International Caries Detection and Assessment System (ICDAS) and Caries Management by Risk Assessment (CABRA). Case report A case is reported of a 14-year-old girl treated for leukaemia who presented with established dental caries lesions which were classified and treated according to ICDAS and CABRA protocols. After three, no new caries was observed. Follow-up and conclusion ICDAS and CAMBRA provide useful and effective guidance for the avoidance of dental and systemic problems. Their introduction into standard practice could reduce the legal difficulties derived from dental treatment in these patients.
Embargo
Aprendizaje basado en problemas (ABP) para la formación odontológica en ciclos formativos de grado medio para cuidados auxiliares en enfermería
(Diego Marín, 2014) Camacho Alonso, Fabio; Sánchez Siles, Mariano; Martínez Beneyto, Yolanda; Dermatología, Estomatología, Radiología y Medicina Física
Open Access
Are denture adhesives safe for oral cells?
(Wiley, 2020-07-12) López García, Sergio; Pecci Lloret, María Pilar; García Bernal, David; Guerrero Gironés, Julia; Pecci Lloret, Miguel Ramón; Rodríguez Lozano, Francisco Javier; Dermatología, Estomatología, Radiología y Medicina Física
Purpose: To compare the cytotoxicity of six commercially available denture adhesives on human gingival cells: Poligrip Flavour Free Fixative Cream, Fixodent Pro Duo Protection, Novafix cream, FittyDent, Polident Total Action, and Fixodent ProPlus Duo Protection. Material and Methods: Eluates of denture adhesives were brought into contact with human gingival cells and compared to untreated cells (w/o any dental adhesive elute). Cell toxicity was assessed by measuring cell viability (3-(4,5-imethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) (MTT) assays), cell morphology (immunofluorescenceassays), induction of apoptosis/necrosis and production of reactive oxygen species (ROS) (flow cytometry assays). In addition, the pH of each sample was determined. Data were analyzed using one-way analysis of variance (ANOVA) followed by Dunnett’s multiple comparisons test. Results: All denture adhesives tested led to a reduction in pH, especially Fixodent Pro Duo Protection and Fixodent Pro Plus Duo Protection. The cell viability assays showed that Fixodent Pro Duo Protection (1:1 72 hours, p = 3.04 × 10−6; 1:2 72 hours, p = 2.07 × 10−6; 1:4 72 hours, p = 2.04 × 10−6) and Fixodent Pro Plus Duo Protection (1:1 72 hours, p = 2.01 × 10−6; 1:2 72 hours, p = 3.03 × 10−6; 1:4 72 hours, p = 2.02 × 10−6) significantly decreased cell viability at all dilutions. Compared to the control group and the rest of the adhesives, Poligrip Flavour Free Fixative Cream (PFF 1:1 72 hours, p = 2.24 × 10−6; 1:2 72 hours, p = 2.44 × 10−6; 1:4 72 hours, p = 2.04 × 10−6) showed a significantly higher cell viability score at all dilutions. Fixodent Pro Duo Protection and Fixodent Pro Plus Duo Protection, both adhesives containing zinc salts in their composition, were responsible for necrosis, and the number of cells was much reduced, with aberrant morphology and pyknotic nucleus. Finally, Fixodent (1:2, p = 2.04 × 10−6, 1:4, p = 0.00036; 1:2, p = 8.82 × 10−6, 1:4, p = 2.30 × 10−6) products significantly promoted ROS production in gingival cells. Conclusions: The results suggest that denture adhesives containing zinc in their composition could be responsible of the decrease of cell viability, ROS production, aberrant cell morphology, and induction of apoptosis and cell death. However, other possible additional cytotoxic factors must be considered. Thus, more studies are necessary to confirm this hypothesis.
Open Access
Association between Pulpal-Periapical Pathology and Autoimmune Diseases: A Systematic Review
(2021) Guerrero Gironés, Julia; Pecci Lloret, María Pilar; Rodríguez Lozano, Francisco Javier; Pecci Lloret, Miguel Ramón; Ros Valverde, Antonio; Dermatología, Estomatología, Radiología y Medicina Física
Several studies have linked apical periodontitis and systemic diseases. The aim of this study is to present a systematic review of the available literature investigating whether there is an association between pulpal-periapical pathology and autoimmune disease. The review was conducted following the PRISMA statement. A literature search was performed in five databases. Studies involving patients with pulpal-periapical pathology and autoimmune diseases were included in the review. Based on the PICO model, the research question aimed to assess whether there is an increased risk of developing pulpal-periapical pathology in patients with autoimmune disease. Article selection, data extraction, and quality assessment were performed using an adapted version of the STROBE guidelines. A total of seven studies were included in our review. The types of articles were five case-control and two cross-sectional studies. Periapical pathologies were associated to three autoimmune diseases (diabetes mellitus I, rheumatoid arthritis, and inflammatory bowel disease). Among the included studies, four show a low risk of bias, while three present a moderate risk. There could be an association between apical periodontitis and autoimmune diseases, although most studies report statistically non-significant associations.
Open Access
Atraumatic maxillary sinus elevation using threaded bone dilators for immediate implants. A three-year clinical study
(Medicina Oral S.L, 2010-03) Calvo Guirado, José Luis; Gómez Moreno, Gerardo; López Marí, Laura; Ortiz Ruiz, Antonio José; Guardia Muñoz, Javier; Dermatología, Estomatología, Radiología y Medicina Física
Objective: The aim of this study was to evaluate the efficacy of sinus floor elevation using sequential bone dilators. Materials and Methods: Thirty patients took part in the study (18 women and 12 men) with ages ranging between thirty-six and sixty-three years, selected according to inclusion and exclusion criteria, who showed a bone deficit in the upper posterior alveolar margin of 5-8 mm in height. Sixty expanded platform internal connection implants were placed with diameters of 4/5/4 mm and lengths varying between 10 (n=10) and 11.5 mm (n= 50). Results: Data obtained were analyzed using SPSS 15.0 software. The average intra-sinus bone gain with MP3 biomaterial of porcine origin was 4.13 +/- 0.97 SD mm at the moment of implant placement, 3.90 +/- 1.15 SD mm after twelve months, 3.74 +/- 1.05 SD mm after 24 months and 3.62 +/- 1.75 SD mm after 36 months. Two implants were lost at the moment of prosthesis placement. Conclusions: Alveolar lifting technique in the upper maxilla using bone dilators achieved a 96.6 % implant success rate after a three-year follow-up. Intra-sinus bone biomaterial remodeling was 0.51 +/- 0.08 mm from day zero to the thirty-six-month follow-up. This is a procedure that reduces the amount of surgery necessary and is of both aesthetic and functional benefit to the patient.