(Murcia : F. Hernández, 1990) Rodríguez Sánchez, F.; Casar, J.; De Castro, J.M.; Del Águila, F.
The distribution and time of appearance of
5HT-storing cells were studied in samples from the
pancreas of mice embryos from 7 to 19 days of gestation.
Additonally, 1- and 15-day-old newborns and adult
specimens were also examined.
Serotonin-immunoreactive cells appeared for the fist
time in the dorsal pancreatic primordium at 10 days of
gestation and increased rapidly in number through E15.
From this age, the cellular number disminished in the
exocrine pancreatic parenchyma, although an increase of
endocrine cells in Wirsung's duct can be detected. At day
15 of extrauterine life, we could only observe some cells
in the surface epithelium of pancreatic duct of Wirsung.
Islet immunoreactive cells could only be detected in
adult animals.