Publication: Comparative histopathological characteristics
of highly pathogenic avian influenza (HPAI) in
chickens and domestic ducks in 2008 Korea
Authors
Woo, G.H. ; Kim, H.Y ; Bae, Y.C. ; Jean, Y.H. ; Bak, E.J. ; Kim, M.J. ; Hwang, E.K. ; Joo, Y.S.
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Publisher
Murcia: F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
We compared characteristic lesions occurring
in chickens and domestic ducks naturally infected with
H5N1 HPAI virus in April and May 2008. Infected
chickens generally exhibited pale-green, watery
diarrhoea, depression, neurological signs and cyanosis of
wattles and combs, and infected ducks generally
exhibited neurological signs and watery diarrhoea. Gross
petechial or ecchymotic haemorrhage affected the heart,
proventriculus, liver, muscle, fat, and pancreas in
chickens, and muscle in ducks. Necrotic foci were
primarily present in the pancreas of both species and in
the heart of domestic ducks. Histopathologically,
chickens exhibited multifocal encephalomalacia,
multifocal lymphohistiocytic myocarditis, multifocal
necrotic pancreatitis and haemorrhage of several organs
and tissues; ducks exhibited lymphohistiocytic
meningoencephalitis with multifocal haemorrhages,
multifocal necrotic pancreatitis, and severe necrotic
myocarditis with mineralisation. The characteristic
histopathologic findings of 2008 HPAI were multifocal
encephalomalacia and necrotic pancreatitis accompanied
by lymphohistiocytic myocarditis, and haemorrhage in
various organs and tissues in chickens, whereas in ducks,
they were severe necrotic myocarditis with
mineralisation and necrotic pancreatitis, accompanied
with lymphohistiocytic meningoencephalitis. The high
mortality of domestic ducks may be intimately
associated with heart failure resulting from increased
H5N1 HPAI viral cardiotropism.
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