Publication: Zinc finger proteins and regulation of the hallmarks of cancer
Authors
Ye, Qin ; Liu, Jiayang ; Xie, Ke
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Publisher
Universidad de Murcia. Departamento de BiologĂa Celular e HistologĂa
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DOI
https://doi.org/10.14670/HH-18-121
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info:eu-repo/semantics/article
Description
Abstract
Zinc finger proteins (ZFPs) form one of the
largest families of transcription factors in human
genetics, via their conserved zinc finger motifs. ZFPs
function in many biological processes including
development, differentiation, metabolism and apoptosis.
In addition, recent studies have demonstrated that ZFPs
are closely associated with different stages of cancer
development. One of the hallmarks of cancer is altered
signal transduction cascades and an understanding of the
changes in these pathways is essential for targeted
cancer therapy. In this review, we discuss examples of
ZFPs involved in development and progression of
several types of cancer, which can provide new insights
into cancer treatment
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Citation
Histology and Histopathology, Vol.34, nÂş10, (2019)
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Este Ătem está sujeto a una licencia Creative Commons. http://creativecommons.org/licenses/by-nc-nd/4.0/