Publication: Primary hepatic malignant fibrous
histiocytoma: A case report and review of the literature
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Date
2007
Authors
Ye, M-F. ; Zheng, S. ; Xu, J.H. ; Chen, L-R.
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Publisher
Murcia: F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Primary malignant fibrous histiocytoma
(MFH) of the liver remains extremely rare with only
several cases having been reported in literature. We
report a case of hepatic MFH in a 53-year-old man who
presented with upper abdominal pain, and weight loss
for one month. Ultrasound and computed tomography
(CT) scan showed a large mass with fine tumor vessels
over the left lobe of the liver. Histopathological findings
indicated a mesenchymal tumor consisting of spindle
cells in storiform pattern intermingled with histiocytelike
cells and giant cells. Immunohistochemically, most
tumor cells expressed vimentin, alpha-1 antichymotrypsin,
alpha-1 antitrypsin and CD68.
Morphological and immunohistochemical findings
support that the tumor should be classified as a primary
malignant fibrous histiocytoma. The literatures is briefly
reviewed.
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