Publication: When one plus one equals more than two - a novel stain for renal biopsies is a combination of two classical stains
Loading...
Date
2010
Authors
Brodsky, Sergey V. ; Albaward, Alia ; Satoskar, Anjali A. ; Nadasdy, Gyongyi ; Nadasdy, Tibor
item.page.secondaryauthor
item.page.director
Publisher
Murcia : F. Hernández
publication.page.editor
publication.page.department
DOI
item.page.type
info:eu-repo/semantics/article
Description
Abstract
Histologic evaluation of renal biopsies
includes multiple ancillary stains, including Periodic
acid-Schiff ’s (PAS) and Masson’s trichrome
(Trichrome). Herein we report an innovative doublestain,
derived from two standard stains (PAS and
Trichrome). This novel stain not only has advantages of
both ancestor stains, but became more distinguishable
and colorful, when basement membranes stain darkviolet,
whereas the interstitial collagen remains blue.
This allows the pathologist immediate estimation of the
amount of collagen, tubular atrophy and the degree of
interstitial fibrosis in one section. Using computer-based
analysis, we confirmed that our innovative double-stain
highlights interstitial collagen better than Trichrome
stain alone. We strongly recommend renal pathologists
to try this innovative stain in their practice.
publication.page.subject
Citation
item.page.embargo
Ir a Estadísticas
Sin licencia Creative Commons.