Publication: Molecular pathogenesis of urothelial bladder cancer
Authors
Theodorescu, D.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Carcinoma of the urinary bladder is the
second most common urologic malignancy. In addition,
these tumors are one of the best understood genitourinary
neoplasms with a well defined etiology, natural
history, tumor biology, treatment options and outcome.
This level of understanding arises as a consequence of
multiple factors and represents a convergence of
knowledge from diverse scientific disciplines. Insight
provided by these disciplines, coupled with unique
features of this neoplasm which make it assessable for
detection, monitoring and treatment, combine to make
this disease a model system for modern oncology. The
intent of this review is to provide the reader an overview
of our current understanding of this tumor from the
standpoint of its molecular biology as related to tumor
development and progression.
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