Publication: DNA repair mechanisms in mammalian germ cells
Authors
Ozturk, Saffet ; Demir, Necdet
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Publisher
Murcia: F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Mammalian germ cells encounter several
types of DNA damage. This damage is almost
completely repaired in a short period of time to provide
the maintenance of genomic integrity. The main repair
mechanisms operating in mammalian germline cells are:
nucleotide excision repair (NER), base excision repair
(BER), mismatch repair (MMR), DNA double strand
break repair (DSBR), and post replication repair (PRR).
Currently, there are relatively few publications that
summarize basic information and new findings on DNA
repair mechanisms used in mammalian germ cells. In the
present article, we review the studies that discuss repair
mechanisms operating in the female and male germ
cells. We then survey some of the recent discoveries
made in this field.
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