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Anti-inflammatory and antifibrotic effects of resveratrol in the lung

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dc.contributor.authorConte, Enrico
dc.contributor.authorFagone, Evelina
dc.contributor.authorFruciano, Mary
dc.contributor.authorGili, Elisa
dc.contributor.authorIemmolo, Maria
dc.contributor.authorVancheri, Carlo
dc.date.accessioned2020-04-20T10:18:08Z
dc.date.available2020-04-20T10:18:08Z
dc.date.issued2015
dc.description.abstractResveratrol, a natural polyphenolic molecule with several biological activities, is a well recognized anti-oxidant, anti-aging and cancer chemopreventive agent. Moreover, resveratrol anti-inflammatory and antifibrotic properties have been demonstrated both in vitro and in different animal models of inflammatory pathologies, including bowel and liver diseases. We review the evidence of resveratrol protective role in respiratory diseases such as acute lung injury, asthma, chronic obstructive pulmonary disease and lung fibrosis. We conclude that resveratrol and its derivatives may act as a therapeutic agents in respiratory diseases and pertinent clinical trials should be performed.es
dc.formatapplication/pdfes
dc.format.extent7es
dc.identifier.doihttps://doi.org/10.14670/HH-30.523
dc.identifier.eisbnHistology and Histopathology, Vol. 30, n.º 5 (2015)es
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/90077
dc.languageenges
dc.publisherF. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histologíaes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAcute lung injuryes
dc.subjectAsthmaes
dc.subjectCOPDes
dc.subjectFibrosises
dc.subject.otherCDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citologíaes
dc.titleAnti-inflammatory and antifibrotic effects of resveratrol in the lunges
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.30, nº5 (2015)