Publication: Identification of protein kinase C α- and tyrosine hydroxylase-immunoreactive cells in the microbat retina
Authors
Park, Eun Bee ; Jeon, Joo Yeong ; Jeon, Chang Jin
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Publisher
Universidad de Murcia. Departamento de Biología Celular e Histología
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DOI
DOI: 10.14670/HH-18-001
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info:eu-repo/semantics/article
Description
Abstract
A growing number of studies have revealed
the functional neuroarchitecture of the microbat retina
and suggested that microbats can see using their eyes. To
better understand the organization of the microbat retina,
quantitative analysis of protein kinase C alpha (PKCα)-
and tyrosine hydroxylase (TH)-immunoreactive (IR)
cells was conducted on the greater horseshoe bat
(Rhinolophus ferrumequinum) retina. As a result, PKCα
immunoreactivity was observed in rod bipolar cells,
consistent with previous studies on other mammalian
retinas. PKCα-IR cell distribution in the inner nuclear
layer showed regional differences in density, with the
highest density found in the nasal retina. The average
density of PKCα-IR cells was 10,487±441 cells/mm2
(mean ± SD; n=4), with a total of 43,077±1,843
cells/retina. TH-IR cells in the Rhinolophus
ferrumequinum retina could be classified into four types
based on soma location and ramification in the inner
plexiform layer: conventional amacrine, displaced
amacrine, interplexiform, and intercalated cells. The
majority of TH-IR cells were conventional amacrine
cells. TH-IR cells were nonrandomly distributed at low
density over the retina. The average density was
29.7±3.1 cells/mm2 (mean ± SD; n=3), with a total of
124.0±11.3 cells/retina. TH-IR processes showed
varicosities and formed ring-like structures encircling
AII amacrine cells. Our study provides the foundation
for understanding the neurochemical architecture of the
microbat retina and supports the notion that the eyes do
play a role in the visual system of microbats.
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Citation
Histology and Histopathology, Vol.33, nº10, (2018)
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