Publication: Neutrophils as a source of cytokines in inflammation
Authors
Matsukawa, A. ; Yoshinaga, M.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The recruitment of neutrophils into
inflammatory foci is a fundamental process observed in
inflammation. The function of neutrophils has long been
regarded only as an effector cell that kills the invading
pathogens. Recent evidence has demonstrated that
neutrophils are capable of producing inflammatory
cytokines. The findings are, however, mainly based on
the findings obtained in vitro. It has not been fully
elucidated if neutrophils could synthesize and secrete
cytokines in vivo. Animal models of inflammation are
essential to address the issue and provide insight into the
involvement of neutrophils in producing cytokines.
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Citation
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