Publication: In situ visualization of o-phthalate esters in
gastrointestinal tract of the frog Rana esculenta
Authors
Menghi, Giovanna ; Marchetti, L. ; Sabbieti, M.G. ; Menghi, M. ; Materazzi, S.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The regional distribution and relative
occurrence of phthalates were studied immunohistochemically
by confocal laser scanning microscopy
in the alimentary tract of the green frog, Rana esculenta,
using an antibody against o-phthalate esters. Many
positive sites indicating the basal presence of phthalate
esters were identified. The immunoreactive cells were
located in the gastric glands of the stomach and in the
intestinal epithelium regions with variable frequencies.
The regional distribution of phathalate-accumulating
cells resembled that of fish and demonstrated that these
endocrine disruptors not only enter via the alimentary
canal, but also bioaccumulate inside cells specialized in
secretion as well as absorption functions.
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