Glycogen autophagy in newborn rat hepatocytes

Publication:
Glycogen autophagy in newborn rat hepatocytes

dc.contributor.author	Kalamidas, Stefanos	es
dc.contributor.author	Kotoulas, Othon B.	es
dc.date.accessioned	2011-02-22T11:22:24Z
dc.date.available	2011-02-22T11:22:24Z
dc.date.issued	2000
dc.description.abstract	Glycogen autophagy in newborn rat hepatocytes was studied by using enzyme determinations and electron microscopy. Cyclic AMP induced glycogen autophagy in these cells. Glycogen-hydrolyzing acid glucosidase activity increased whereas acid mannose 6- phosphatase activity decreased in the liver of these animals. Parenteral glucose, which prevents postnatal glucagon secretion and tissue cyclic AMP elevation, and propranolol which antagonizes cyclic AMP, inhibited glycogen autophagy. Glucosidase activity decreased and phosphatase activity increased. These findings raise the possibility that cyclic AMP-induced autophagic mechanisms in newborn rat hepatocytes are associated with changes in the activity of acid mannose 6- phosphatase.	es
dc.format	application/pdf	es
dc.format.extent	8	es
dc.identifier.issn	0213-3911	es
dc.identifier.uri	http://hdl.handle.net/10201/19353
dc.language	eng	es
dc.publisher	Murcia : F. Hernández	es
dc.relation.ispartof	Histology and histopathology	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Glycogen autophagy	es
dc.subject	Acid glucosidase	es
dc.subject.other	CDU::6 - Ciencias aplicadas::61 - Medicina	es
dc.title	Glycogen autophagy in newborn rat hepatocytes	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es

Now showing 1 - 1 of 1

Sin licencia Creative Commons.