Publication: Effects of bombesin on the morphology and
Authors
Malendowicz, L.K. ; Nussdorfer, G.G. ; Miskowiak, B. ; Majchrzak, M.
item.page.secondaryauthor
item.page.director
Publisher
Murcia : F. Hernández
publication.page.editor
publication.page.department
DOI
item.page.type
info:eu-repo/semantics/article
Description
Abstract
The acute and chronic effects of bornbesin
(BM) on the structure and function of rat adrenal
cortex were investigated by rnorphornetric and
radioirnrnunological techniques. An intraperitoneal bolus
injection of 2 yglrat BM rnarkedly raised plasma
corticosterone (B) concentration (PBC). The intraperitoneal
BM infusion (1 yg/rat.h-l) for 1, 2 or 4
days evoked a notable increase in the nurnber of
adrenocortical cells, without inducing apparent changes
in either PBC or B output by adrenal quarters. Since
proliferation and expression of specialized functions are
rnutually exclusive states of cells, our findings suggest
that the conspicuous stirnulation of adrenocortical-cell
proliferation evoked by BM infusion may be responsible
for the apparent lack of effect of this treatrnent on B
secretion.
publication.page.subject
Citation
item.page.embargo
Ir a Estadísticas
Sin licencia Creative Commons.