Publication: Tumor heterogeneity has important consequences
for personalized medicine in ovarian cancer
Authors
Gui, Ting ; Cao, Dongyan ; Yang, Jiaxin ; Shen, Keng
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Publisher
F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología
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DOI
https://doi.org/10.14670/HH-30.173
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info:eu-repo/semantics/article
Description
Abstract
Most patients with ovarian cancers relapse,
and treatment failure has often been attributed to
chemoresistance in tumor cells. Emerging evidence
indicates that tumor heterogeneity may play an equally
important role. Although the idea of tumor heterogeneity
is not new, little attention has been focused on applying
it to understand and control ovarian cancer progression.
Recent advances in understanding its generation model,
original basis, consequent problems, and derived
therapies provide great potential for tumor heterogeneity
to be a new insight in treatment of ovarian cancers.
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Citation
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