Publication: Histopathology of human small intestinal and colonic ischemia-reperfusion: Experiences from human IR-models
Authors
Leenarts, Claire A.J.I. ; Grootjans, Joep ; Hundscheid, Inca H. ; Schellekens, Dirk H.S.M. ; Lenaerts, Kaatje ; Buurman, Wim A. ; Dejong, Cornelis H.C. ; Derikx, Joep P.M.
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Publisher
Universidad de Murcia. Departamento de Biología Celular e Histología
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DOI
DOI: 10.14670/HH-18-074
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info:eu-repo/semantics/article
Description
Abstract
Intestinal ischemia-reperfusion (IR) injury is
a frequent, but potentially life-threatening condition.
Although much has been learned about its
pathophysiology from animal IR models, the translation
to the human setting is imperative for better
understanding of its etiology. This could provide us with
new insight into development of early detection and
potential new therapeutic strategies. Over the past
decade, we have studied the pathophysiology of human
small intestinal and colonic ischemia-reperfusion (IR) in
newly developed human in vivo IR models. In this
review, we give an overview of new insights on the
sequelae of human intestinal IR, with particular attention
for the differences in histopathology between small
intestinal and colonic IR.
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Citation
Histology and Histopathology, Vol.34, nº7, (2019)
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Este ítem está sujeto a una licencia Creative Commons. http://creativecommons.org/licenses/by-nc-nd/4.0/