Publication: Bronchial epithelium associated to lymphoid tissue does not selectively express vimentin
Authors
Alonso, L.M. ; Cortés, A. ; Barrutia, M.G. ; Romo, T. ; Varas, A. ; Zapata, A.G.
item.page.secondaryauthor
item.page.director
Publisher
Murcia : F. Hernández
publication.page.editor
publication.page.department
Description
Abstract
The existence of a lymphoepithelium
containing M cells in the bronchus-assmiated lymphoid
tissue (BALT) of severa1 species has repeatedly been
questioned. In previous electron microscopical studies
we failed to ultrastmcturally identify these cells in the
epithelium covering bronchial lymphoid tissue of adult
rats. In the present study, we analyze immunohistochemically
the expression of vimentin, an intermediate
filament, reported to be a sensitive marker for rabbit M
cells, in both BALT and Peyer's patches. Our results
demonstrate, however, the absence of vimentin
expression in the epithelium covering the bronchial
lymphoid aggregates as well as in the lymphoepithelium
of the Peyer's patches. On the contrary, both epithelia are
strongly cytokeratin positive. Furthermore, numerous
vimentin-positive lymphocytes appear in both lymphoid
organs. Results are discussed from a view of the possible
relationship between BALT and the so-called mucosaeassociated
lymphoid tissue (MALT).
publication.page.subject
Citation
item.page.embargo
Ir a Estadísticas
Sin licencia Creative Commons.