Publication: Papillary adenoma of the kidney with mucinous secretion
Authors
Val-Bernal, José Fernando ; Pinto, J. ; Gómez-Román, J.J. ; Mayorga, M. ; Villoria, F.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Although infrequently, mucin secretion has
previously been reported in papillary renal cell
carcinoma. We here investigate the presence of mucin in
a series of 93 renal papillary adenomas in 58 patients.
Acid mucin was present in four cases (4.3% of the
tumors; 6.9% of the patients), in which basophilic mucin
secretion was evident with hematoxylin-eosin. To the
best of our knowledge mucin secretion has not been
reported in renal papillary adenoma. We describe two
different types of mucin secretion: intracytoplasmic and
luminal. The secretion was intracellular in numerous
scattered tumor cells in two cases, foca1 luminal in one
case, and mixed intracellular and luminal in another
case. Mucin production, despite its low frequency, can
be considered as an additional feature of renal papillary
adenoma. Mucin production suggests that renal papillary
adenoma and papillary renal cell carcinoma are actually
not two independent biological processes, but a
continuum of one biological process.
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Citation
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