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10.14670/HH-11-637
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Xiao, Meng | - |
dc.contributor.author | Wang, Xu | - |
dc.contributor.author | Chen, Wantao | - |
dc.date.accessioned | 2020-12-16T11:55:54Z | - |
dc.date.available | 2020-12-16T11:55:54Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Histology and Histopathology, vol. 30, nº 10, (2015) | es |
dc.identifier.issn | 1699-5848 | - |
dc.identifier.issn | 0213-3911 | - |
dc.identifier.uri | http://hdl.handle.net/10201/99969 | - |
dc.description.abstract | We aimed to analyse and summarise the potential value of the clinical use of p53-related alterations as cancer biomarkers. A systematic search and collection of the published meta-analyses on p53- related alterations and cancers in the past 5 years was conducted through appropriate queries in the PubMed database. We then composed “grey-scale” tables to show the significant levels for each variant, and the potential heterogeneity was subsequently discussed. The data show that p53-related alterations are extremely complex biomarkers in terms of their clinical translation. Together with the experimental studies on p53-related alterations, a gold-standard approach is still in need of development, with more evidence from clinical studies with large, prospectively planned cohorts, to fully understand its potential as a cancer biomarker. | es |
dc.format | application/pdf | es |
dc.format.extent | 18 | es |
dc.language | eng | es |
dc.publisher | F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología | es |
dc.relation | Sin financiación externa a la Universidad | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | p53 | es |
dc.subject | Meta-analysis | es |
dc.subject | Cancer biomarker | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología | es |
dc.title | The clinical translational potential of p53-related alterations as cancer biomarkers | es |
dc.type | info:eu-repo/semantics/article | es |
dc.identifier.doi | 10.14670/HH-11-637 | - |
Aparece en las colecciones: | Vol.30,nº10 (2015) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Xiao-30-1171-1183-2015.pdf | 875,22 kB | Adobe PDF | Visualizar/Abrir |
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