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Título: | Arterial wall neovascularization induced by glycerol |
Fecha de publicación: | 2001 |
Editorial: | F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología |
Cita bibliográfica: | Histology and histopathology, Vol. 16, nº 4 (2001) |
ISSN: | 1699-5848 0213-3911 |
Materias relacionadas: | CDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citología |
Palabras clave: | Arterial wall Angiogenesis Glycerol Smooth muscle cells Pericytes Neovascularization |
Resumen: | An int e nse a nd sig ni fica nt neo - vascul ari za tion, with numerous capillaries growing into th e med ia laye r o f th e rat femo ra l art e ry, was demonstrated when glycero l was administered into the interstitium be tween the femoral ve in and the femoral a rt e ry. Th e max imum mi c rovasc ul a ri za ti o n was obse rved at days 7 and 9 after glyce rol administration. Afterwards, invo lution of th e majo rit y of the new lyfo rmed microvessels in the art erial wall occurred. Other substances containing glyce rol in their molecul es, such as tri ace tyl-glyce rol and tri butyril-glyce rol, fa il ed to produce significant neovascul ari zation in the medi a laye r of the femora l art ery. Neova cul ariza tion of the art eri al wa ll was preceded by a co nside rab le dec rease in the number of the smooth muscle ce lls, whi ch ex perienced apoptosis and necrobiosis, disappearing in extense areas of the arteri al segment affected by glyce rol. Coinciding with neovascul ariza tion and mi crovascul ar in volu tion, repopul ation of the med ia laye r by smooth mu 'cle cells was observed. |
Autor/es principal/es: | Díaz Flores, L. Madrid, J. F. Gutierrez, R. Valladares, F. Díaz, M. Valera, H. Díaz Flores Jr, L. |
URI: | http://hdl.handle.net/10201/96151 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 7 |
Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 International |
Aparece en las colecciones: | Vol.16, nº 4 (2001) |
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