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Título: | Mechanism of experimental autoimmune neuritis in Lewis rats: the dual role of macrophages |
Fecha de publicación: | 2013 |
Editorial: | F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología |
Cita bibliográfica: | Histology and Histopathology, vol. 28, nº 6, (2013) |
ISSN: | 1699-5848 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
Palabras clave: | Alternatively activated macrophages Experimental autoimmune neuritis Guillain-Barré syndrome Peripheral nervous system inflammation |
Resumen: | Human peripheral demyelinating diseases, such as Guillain-Barré syndrome (GBS), are characterized by inflammation and demyelination in the peripheral nervous system. Similarities in the pathology between GBS and the animal model of experimental autoimmune neuritis (EAN) indicate that autoimmune responses are involved in both diseases. This article summarizes the general aspects of the EAN model in Lewis rats and discusses the potential role of macrophages in the progression of EAN. A better understanding of macrophages may help to design alternative therapeutic strategies for organ-specific autoimmune diseases, including GBS. |
Autor/es principal/es: | Shin, Taekyun Ahn, Meejung Matsumoto, Yoh Moon, Changjong |
URI: | http://hdl.handle.net/10201/58401 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 6 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.28, nº 6 (2013) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Shin-28-679-684-2013.pdf | 115,32 kB | Adobe PDF | Visualizar/Abrir |
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